Dual fragmentation via collision-induced and oxygen attachment dissociations using water and its radicals for C=C position-resolved lipidomics
Abstract Oxygen attachment dissociation (OAD) is a tandem mass spectrometry (MS/MS) technique for annotating the positions of double bonds (C=C) in complex lipids. Although OAD has been used for untargeted lipidomics, its availability has been limited to the positive ion mode, requiring the independ...
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| Main Authors: | Hiroaki Takeda, Mami Okamoto, Hidenori Takahashi, Bujinlkham Buyantogtokh, Noriyuki Kishi, Hideyuki Okano, Hiroyuki Kamiguchi, Hiroshi Tsugawa |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Communications Chemistry |
| Online Access: | https://doi.org/10.1038/s42004-025-01525-y |
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