Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury
Traumatic brain injury (TBI) triggers a robust inflammatory response that is closely linked to worsened clinical outcomes. S100A8/A9, also known as calprotectin or myeloid-related protein-8/14 (MRP8/14), is an alarmin primarily secreted by activated neutrophils with potent pro-inflammatory property....
Saved in:
Main Authors: | Guihong Shi, Yiyao Cao, Jianye Xu, Bo Chen, Xu Zhang, Yanlin Zhu, Liang Liu, Xilei Liu, Luyuan Zhang, Yuan Zhou, Shenghui Li, Guili Yang, Xiao Liu, Fanglian Chen, Xin Chen, Jianning Zhang, Shu Zhang |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-04-01
|
Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221323172500045X |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
β2 integrin regulates neutrophil trans endothelial migration following traumatic brain injury
by: Lei Li, et al.
Published: (2025-02-01) -
S100A9 protein activates microglia and stimulates phagocytosis, resulting in synaptic and neuronal loss
by: Katryna Pampuscenko, et al.
Published: (2025-03-01) -
Evaluation of S100A8/A9 and neutrophils as prognostic markers in metastatic melanoma patients under immune-checkpoint inhibition
by: Yasmin F Melzer, et al.
Published: (2025-02-01) -
Neutrophil Extracellular Traps Contribute to the Disease Severity of Dengue Virus Infection
by: Cucunawangsih Cucunawangsih, et al.
Published: (2024-08-01) -
Mfsd2a suppresses colorectal cancer progression and liver metastasis via the S100A14/STAT3 axis
by: Linfeng Sun, et al.
Published: (2025-01-01)