Dynamically customizable 4D printed shape memory polymer biomedical devices: a review
There is an increased risk of complications and even surgical failures for various types of medical devices due to difficult to control configurations and performances, incomplete deployments, etc. Shape memory polymers (SMPs)-based 4D printing technology offers the opportunity to create dynamic, pe...
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| Format: | Article |
| Language: | English |
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IOP Publishing
2025-01-01
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| Series: | Materials Futures |
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| Online Access: | https://doi.org/10.1088/2752-5724/ad8898 |
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| author | Xiaozhou Xin Cheng Lin Xiaofei Wang Fukai Liu Lili Dong Liwu Liu Yanju Liu Jinsong Leng |
| author_facet | Xiaozhou Xin Cheng Lin Xiaofei Wang Fukai Liu Lili Dong Liwu Liu Yanju Liu Jinsong Leng |
| author_sort | Xiaozhou Xin |
| collection | DOAJ |
| description | There is an increased risk of complications and even surgical failures for various types of medical devices due to difficult to control configurations and performances, incomplete deployments, etc. Shape memory polymers (SMPs)-based 4D printing technology offers the opportunity to create dynamic, personalized, and accurately controllable biomedical devices with complex configurations. SMPs, typical representatives of intelligent materials, are capable of programmable deformation in response to stimuli and dynamic remodeling on demand. 4D printed SMP medical devices not only enable active control of configuration, performance and functionality, but also open the way for minimally invasive treatments and remote controllable deployment. Here, the shape memory mechanism, actuation methods, and printing strategies of active programmable SMPs are reviewed, and cutting-edge advances of 4D printed SMPs in the fields such as bone scaffolds, tracheal stents, cardiovascular stents, cell morphological regulation, and drug delivery are highlighted. In addition, promising and meaningful future research directions for 4D printed SMP biomedical devices are discussed. The development of 4D printed SMP medical devices is inseparable from the in-depth cooperation between doctors and engineers. The application of 4D printed SMP medical devices will facilitate the rapid realization of ‘smart medical care’ and accelerate the process of ‘intelligentization’ of medical devices. |
| format | Article |
| id | doaj-art-ed903d1e0afe48d3aa1d86281bfbaa48 |
| institution | OA Journals |
| issn | 2752-5724 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | Materials Futures |
| spelling | doaj-art-ed903d1e0afe48d3aa1d86281bfbaa482025-08-20T01:47:47ZengIOP PublishingMaterials Futures2752-57242025-01-014101240210.1088/2752-5724/ad8898Dynamically customizable 4D printed shape memory polymer biomedical devices: a reviewXiaozhou Xin0Cheng Lin1Xiaofei Wang2Fukai Liu3Lili Dong4Liwu Liu5Yanju Liu6https://orcid.org/0000-0001-8269-1594Jinsong Leng7Department of Astronautical Science and Mechanics, Harbin Institute of Technology , Harbin, People’s Republic of ChinaCentre for Composite Materials and Structures, Harbin Institute of Technology , Harbin, People’s Republic of ChinaCentre for Composite Materials and Structures, Harbin Institute of Technology , Harbin, People’s Republic of ChinaAnimal Laboratory Center, The First Affiliated Hospital of Harbin Medical University , Harbin, People’s Republic of ChinaAnimal Laboratory Center, The First Affiliated Hospital of Harbin Medical University , Harbin, People’s Republic of ChinaDepartment of Astronautical Science and Mechanics, Harbin Institute of Technology , Harbin, People’s Republic of ChinaDepartment of Astronautical Science and Mechanics, Harbin Institute of Technology , Harbin, People’s Republic of ChinaCentre for Composite Materials and Structures, Harbin Institute of Technology , Harbin, People’s Republic of ChinaThere is an increased risk of complications and even surgical failures for various types of medical devices due to difficult to control configurations and performances, incomplete deployments, etc. Shape memory polymers (SMPs)-based 4D printing technology offers the opportunity to create dynamic, personalized, and accurately controllable biomedical devices with complex configurations. SMPs, typical representatives of intelligent materials, are capable of programmable deformation in response to stimuli and dynamic remodeling on demand. 4D printed SMP medical devices not only enable active control of configuration, performance and functionality, but also open the way for minimally invasive treatments and remote controllable deployment. Here, the shape memory mechanism, actuation methods, and printing strategies of active programmable SMPs are reviewed, and cutting-edge advances of 4D printed SMPs in the fields such as bone scaffolds, tracheal stents, cardiovascular stents, cell morphological regulation, and drug delivery are highlighted. In addition, promising and meaningful future research directions for 4D printed SMP biomedical devices are discussed. The development of 4D printed SMP medical devices is inseparable from the in-depth cooperation between doctors and engineers. The application of 4D printed SMP medical devices will facilitate the rapid realization of ‘smart medical care’ and accelerate the process of ‘intelligentization’ of medical devices.https://doi.org/10.1088/2752-5724/ad88984D printingshape memory polymersbiomedical devicestissue engineering scaffolds |
| spellingShingle | Xiaozhou Xin Cheng Lin Xiaofei Wang Fukai Liu Lili Dong Liwu Liu Yanju Liu Jinsong Leng Dynamically customizable 4D printed shape memory polymer biomedical devices: a review Materials Futures 4D printing shape memory polymers biomedical devices tissue engineering scaffolds |
| title | Dynamically customizable 4D printed shape memory polymer biomedical devices: a review |
| title_full | Dynamically customizable 4D printed shape memory polymer biomedical devices: a review |
| title_fullStr | Dynamically customizable 4D printed shape memory polymer biomedical devices: a review |
| title_full_unstemmed | Dynamically customizable 4D printed shape memory polymer biomedical devices: a review |
| title_short | Dynamically customizable 4D printed shape memory polymer biomedical devices: a review |
| title_sort | dynamically customizable 4d printed shape memory polymer biomedical devices a review |
| topic | 4D printing shape memory polymers biomedical devices tissue engineering scaffolds |
| url | https://doi.org/10.1088/2752-5724/ad8898 |
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