Orexin-A and motion sickness: a systematic review of animal model studies

Orexin-A and motion sickness: a systematic review of animal model studies

BackgroundSensory input mismatches among the vestibular system, autonomic control, and visual perception cause motion sickness. Anticholinergics and antihistamines are commonly used but have limited efficacy and cause significant side effects. Orexin-A, a hypothalamic neuropeptide, has recently garn...

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Bibliographic Details
Main Authors:	Xu Cai, Long Zhao, Xin Wang, Jiahui Chen, Ying Yuan, Biao Gao, Yanli You
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Pharmacology
Subjects:	orexin-A motion sickness systematic review neural mechanisms therapeutic potential
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1624080/full
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