Development and validation of a disulfidptosis-related genes signature for predicting outcomes and immunotherapy in acute myeloid leukemia

Development and validation of a disulfidptosis-related genes signature for predicting outcomes and immunotherapy in acute myeloid leukemia

BackgroundAcute myeloid leukemia (AML) is a hematopoietic malignancy with poor outcomes and high recurrence. Disulfidptosis, a novel form of programmed cell death driven by aberrant disulfide bonds and F-actin collapse, provides insights into cancer progression and treatment.MethodsWe investigated t...

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Bibliographic Details
Main Authors: Han Gong, Ying Zhang, Xusheng Wu, Yiming Pan, Mingwei Wang, Xiaofeng He, Jing Liu, Zhong Liu, Ling Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
acute myeloid leukemia
disulfidptosis-related genes
prognosis
risk model
immunomodulation
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1513040/full
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