Quality of life in patients with chronic liver disease
Background/Aim. Quality of life is impaired in patients with the chronic liver disease (CLD). Patients with this disease have numerous disabling problems which lead to a reduced health related quality of life (HRQoL). The aim of our study was to evaluate the predictive value of selected socio-demogr...
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2018-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600339P.pdf |
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| author | Popović Dušan Đ. Kisić-Tepavčević Darija Kovačević Nada Milovanović Tamara Krstić Miodrag Ranković Ivan Martinov Jelena Glišić Tijana Ješić Rada Pekmezović Tatjana |
| author_facet | Popović Dušan Đ. Kisić-Tepavčević Darija Kovačević Nada Milovanović Tamara Krstić Miodrag Ranković Ivan Martinov Jelena Glišić Tijana Ješić Rada Pekmezović Tatjana |
| author_sort | Popović Dušan Đ. |
| collection | DOAJ |
| description | Background/Aim. Quality of life is impaired in patients with the chronic liver disease (CLD). Patients with this disease have numerous disabling problems which lead to a reduced health related quality of life (HRQoL). The aim of our study was to evaluate the predictive value of selected socio-demographic and clinical characteristics on HRQoL in Serbian cohort of patients with the CLD. Methods. Over a period of one year, we performed a study which included patients with the CLD. We used Short Form Health Survay-36 (SF-36) for assessment of HRQoL. The assessment of depression and anxiety was made by using Hamilton scale of depression and anxiety, while the assessment of fatigue was performed by Fatigue severity scale. Results. The study included 103 patients with the CLD. The average values of the overall SF-36 scores were 52.6 ± 20.4, while the mean score of the composite scores were 53.5 ± 19.6 for the Mental component summary and 49.8 ± 21.3 for the Physical component summary. Some domains of HRQoL were significantly affected by following factors: gender, age, employment status, alcohol consumption, depression, anxiety and fatigue. Predictors of physical components of HRQoL were employment, depression and fatigue, and predictors of mental components were depression and fatigue. Conclusion. The tested socio-demographic, clinical and behavioral factors have an impact on the HRQoL in patients with the CLD. The most important predictors of HRQoL are behavioral factors suggesting the need for an adequate therapeutic action in order to improve the HRQoL in these patients. |
| format | Article |
| id | doaj-art-ed8a6a63586f490481944c9222dff5e5 |
| institution | OA Journals |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-ed8a6a63586f490481944c9222dff5e52025-08-20T02:22:09ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202018-01-0175545346010.2298/VSP160616339P0042-84501600339PQuality of life in patients with chronic liver diseasePopović Dušan Đ.0Kisić-Tepavčević Darija1Kovačević Nada2Milovanović Tamara3Krstić Miodrag4Ranković Ivan5Martinov Jelena6Glišić Tijana7Ješić Rada8Pekmezović Tatjana9Clinical Centre of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade + Faculty of Medicine, Belgrade Faculty of Medicine, Belgrade + Institute of Epidemiology, BelgradeClinical Centre of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade + Faculty of Medicine, Belgrade Clinical Centre of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade + Faculty of Medicine, Belgrade Clinical Centre of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade + Faculty of Medicine, Belgrade Clinical Centre of Serbia, Clinic for Gastroenterology and Hepatology, BelgradeClinical Centre of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade + Faculty of Medicine, Belgrade Clinical Centre of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade + Faculty of Medicine, Belgrade Clinical Centre of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade + Faculty of Medicine, BelgradeFaculty of Medicine, Belgrade + Institute of Epidemiology, BelgradeBackground/Aim. Quality of life is impaired in patients with the chronic liver disease (CLD). Patients with this disease have numerous disabling problems which lead to a reduced health related quality of life (HRQoL). The aim of our study was to evaluate the predictive value of selected socio-demographic and clinical characteristics on HRQoL in Serbian cohort of patients with the CLD. Methods. Over a period of one year, we performed a study which included patients with the CLD. We used Short Form Health Survay-36 (SF-36) for assessment of HRQoL. The assessment of depression and anxiety was made by using Hamilton scale of depression and anxiety, while the assessment of fatigue was performed by Fatigue severity scale. Results. The study included 103 patients with the CLD. The average values of the overall SF-36 scores were 52.6 ± 20.4, while the mean score of the composite scores were 53.5 ± 19.6 for the Mental component summary and 49.8 ± 21.3 for the Physical component summary. Some domains of HRQoL were significantly affected by following factors: gender, age, employment status, alcohol consumption, depression, anxiety and fatigue. Predictors of physical components of HRQoL were employment, depression and fatigue, and predictors of mental components were depression and fatigue. Conclusion. The tested socio-demographic, clinical and behavioral factors have an impact on the HRQoL in patients with the CLD. The most important predictors of HRQoL are behavioral factors suggesting the need for an adequate therapeutic action in order to improve the HRQoL in these patients.http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600339P.pdfliver diseaseshepatic insufficiencyquality of lifeserbiasociological factorsdemographydepressionsurveys and questionnaires |
| spellingShingle | Popović Dušan Đ. Kisić-Tepavčević Darija Kovačević Nada Milovanović Tamara Krstić Miodrag Ranković Ivan Martinov Jelena Glišić Tijana Ješić Rada Pekmezović Tatjana Quality of life in patients with chronic liver disease Vojnosanitetski Pregled liver diseases hepatic insufficiency quality of life serbia sociological factors demography depression surveys and questionnaires |
| title | Quality of life in patients with chronic liver disease |
| title_full | Quality of life in patients with chronic liver disease |
| title_fullStr | Quality of life in patients with chronic liver disease |
| title_full_unstemmed | Quality of life in patients with chronic liver disease |
| title_short | Quality of life in patients with chronic liver disease |
| title_sort | quality of life in patients with chronic liver disease |
| topic | liver diseases hepatic insufficiency quality of life serbia sociological factors demography depression surveys and questionnaires |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600339P.pdf |
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