Role of liver transient elastography in detecting cirrhosis with esophageal and gastric varices and evaluating variceal severity
Abstract Objective To explore the application and clinical value of liver transient elastography (TE) in diagnosing and assessing the degree of liver cirrhosis combined with esophageal and gastric varices (EGV). Methods We chose 136 patients with cirrhosis and EGV admitted to the Liver Disease Depar...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
|
| Series: | BMC Gastroenterology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12876-025-03982-0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849309769410543616 |
|---|---|
| author | Chaozhi Wang |
| author_facet | Chaozhi Wang |
| author_sort | Chaozhi Wang |
| collection | DOAJ |
| description | Abstract Objective To explore the application and clinical value of liver transient elastography (TE) in diagnosing and assessing the degree of liver cirrhosis combined with esophageal and gastric varices (EGV). Methods We chose 136 patients with cirrhosis and EGV admitted to the Liver Disease Department of our hospital from December 2022 to December 2024. The patients were divided into mild EGV (n = 71), moderate EGV (n = 40), and severe EGV (n = 25) based on the gastroscopic results, and another 50 cases of healthy physical examination at the same period were admitted into the control group. All cases underwent liver TE, biochemical parameters, and immune parameters examination to observe the diagnostic efficacy of liver TE in cirrhosis combined with EGV and the degree of varices. Results The differences in TBIL, ALT, AST, PTA, and other biochemical parameters between all of groups were not statistically significant (P > 0.05). The differences were not statistically significant for the four groups of IgM, IgG, and other immune indices (P > 0.05). There was no significant difference in blood flow among these groups (P > 0.05). The interior diameter (ID) of the portal vein, blood flow velocity, and liver stiffness values were significant (P < 0.05). Portal vein ID, blood velocity, and liver stiffness values showed well diagnostic efficacy in cirrhosis with EGV, and liver stiffness values were the best in evaluating cirrhosis with EGV (P < 0.05). Liver stiffness values were more effective in assessing the degree of varices in cirrhosis combined with EGV and the best in diagnosing cirrhosis combined with severe EGV (P < 0.05). Conclusion The application of liver TE has a high value in diagnosing cirrhosis combined with EGV and their degree of varices, especially in identifying severe curves, which has good clinical value. |
| format | Article |
| id | doaj-art-ed7e626c4d974dfbbcbcbe22bee6b4b7 |
| institution | Kabale University |
| issn | 1471-230X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj-art-ed7e626c4d974dfbbcbcbe22bee6b4b72025-08-20T03:53:58ZengBMCBMC Gastroenterology1471-230X2025-05-012511910.1186/s12876-025-03982-0Role of liver transient elastography in detecting cirrhosis with esophageal and gastric varices and evaluating variceal severityChaozhi Wang0Department of Gastroenterology, 3201 Hospital Affiliated to Xi ’an Jiaotong University School of MedicineAbstract Objective To explore the application and clinical value of liver transient elastography (TE) in diagnosing and assessing the degree of liver cirrhosis combined with esophageal and gastric varices (EGV). Methods We chose 136 patients with cirrhosis and EGV admitted to the Liver Disease Department of our hospital from December 2022 to December 2024. The patients were divided into mild EGV (n = 71), moderate EGV (n = 40), and severe EGV (n = 25) based on the gastroscopic results, and another 50 cases of healthy physical examination at the same period were admitted into the control group. All cases underwent liver TE, biochemical parameters, and immune parameters examination to observe the diagnostic efficacy of liver TE in cirrhosis combined with EGV and the degree of varices. Results The differences in TBIL, ALT, AST, PTA, and other biochemical parameters between all of groups were not statistically significant (P > 0.05). The differences were not statistically significant for the four groups of IgM, IgG, and other immune indices (P > 0.05). There was no significant difference in blood flow among these groups (P > 0.05). The interior diameter (ID) of the portal vein, blood flow velocity, and liver stiffness values were significant (P < 0.05). Portal vein ID, blood velocity, and liver stiffness values showed well diagnostic efficacy in cirrhosis with EGV, and liver stiffness values were the best in evaluating cirrhosis with EGV (P < 0.05). Liver stiffness values were more effective in assessing the degree of varices in cirrhosis combined with EGV and the best in diagnosing cirrhosis combined with severe EGV (P < 0.05). Conclusion The application of liver TE has a high value in diagnosing cirrhosis combined with EGV and their degree of varices, especially in identifying severe curves, which has good clinical value.https://doi.org/10.1186/s12876-025-03982-0Liver transient elastographyLiver cirrhosisEsophageal and gastric varicesDiagnosisApplication |
| spellingShingle | Chaozhi Wang Role of liver transient elastography in detecting cirrhosis with esophageal and gastric varices and evaluating variceal severity BMC Gastroenterology Liver transient elastography Liver cirrhosis Esophageal and gastric varices Diagnosis Application |
| title | Role of liver transient elastography in detecting cirrhosis with esophageal and gastric varices and evaluating variceal severity |
| title_full | Role of liver transient elastography in detecting cirrhosis with esophageal and gastric varices and evaluating variceal severity |
| title_fullStr | Role of liver transient elastography in detecting cirrhosis with esophageal and gastric varices and evaluating variceal severity |
| title_full_unstemmed | Role of liver transient elastography in detecting cirrhosis with esophageal and gastric varices and evaluating variceal severity |
| title_short | Role of liver transient elastography in detecting cirrhosis with esophageal and gastric varices and evaluating variceal severity |
| title_sort | role of liver transient elastography in detecting cirrhosis with esophageal and gastric varices and evaluating variceal severity |
| topic | Liver transient elastography Liver cirrhosis Esophageal and gastric varices Diagnosis Application |
| url | https://doi.org/10.1186/s12876-025-03982-0 |
| work_keys_str_mv | AT chaozhiwang roleoflivertransientelastographyindetectingcirrhosiswithesophagealandgastricvaricesandevaluatingvaricealseverity |