Lessons Learned from a Small Pediatric Continuous Renal Replacement Therapy Program

Continuous renal replacement therapy (CRRT) has become a pillar of care in pediatric intensive care units (PICUs) over the past few decades. Quality indicators (QIs) have been evaluated that reflect safe and accountable CRRT. However, there is a paucity of data on outcomes and QIs in smaller-volume...

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Main Authors: Tanya Holt, Olivia Griffin, Amelie Cyr, Rebecca Brockman, Laura Wihak, Gregory Hansen
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Critical Care Research and Practice
Online Access:http://dx.doi.org/10.1155/2021/6481559
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author Tanya Holt
Olivia Griffin
Amelie Cyr
Rebecca Brockman
Laura Wihak
Gregory Hansen
author_facet Tanya Holt
Olivia Griffin
Amelie Cyr
Rebecca Brockman
Laura Wihak
Gregory Hansen
author_sort Tanya Holt
collection DOAJ
description Continuous renal replacement therapy (CRRT) has become a pillar of care in pediatric intensive care units (PICUs) over the past few decades. Quality indicators (QIs) have been evaluated that reflect safe and accountable CRRT. However, there is a paucity of data on outcomes and QIs in smaller-volume CRRT programming. The purpose of this retrospective study was to evaluate the efficiencies, effectiveness, and outcomes of a small-volume CRRT program. Eighty-two patients received CRRT over a 13-year period, and 79% survived to discharge. Sepsis or nonseptic shock (n = 11 (22%) versus n = 6 (50%); p value = 0.004) and time to CRRT initiation after PICU admission (1.1 versus 5.0 days; p value = 0.005) were independent predictors for mortality. The program also had positive outcomes for QIs related to CRRT efficiency and time of initiation, dosing delivery, and rate of adverse events. This study is important as it illustrates the opportunity that smaller centers have to initiate CRRT programming and provide safe and effective care.
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spelling doaj-art-ed7d753c00984fc293714ade8e09a0c32025-08-20T03:21:11ZengWileyCritical Care Research and Practice2090-13132021-01-01202110.1155/2021/6481559Lessons Learned from a Small Pediatric Continuous Renal Replacement Therapy ProgramTanya Holt0Olivia Griffin1Amelie Cyr2Rebecca Brockman3Laura Wihak4Gregory Hansen5Jim Pattison Children’s HospitalCollege of MedicineCollege of MedicineJim Pattison Children’s HospitalJim Pattison Children’s HospitalJim Pattison Children’s HospitalContinuous renal replacement therapy (CRRT) has become a pillar of care in pediatric intensive care units (PICUs) over the past few decades. Quality indicators (QIs) have been evaluated that reflect safe and accountable CRRT. However, there is a paucity of data on outcomes and QIs in smaller-volume CRRT programming. The purpose of this retrospective study was to evaluate the efficiencies, effectiveness, and outcomes of a small-volume CRRT program. Eighty-two patients received CRRT over a 13-year period, and 79% survived to discharge. Sepsis or nonseptic shock (n = 11 (22%) versus n = 6 (50%); p value = 0.004) and time to CRRT initiation after PICU admission (1.1 versus 5.0 days; p value = 0.005) were independent predictors for mortality. The program also had positive outcomes for QIs related to CRRT efficiency and time of initiation, dosing delivery, and rate of adverse events. This study is important as it illustrates the opportunity that smaller centers have to initiate CRRT programming and provide safe and effective care.http://dx.doi.org/10.1155/2021/6481559
spellingShingle Tanya Holt
Olivia Griffin
Amelie Cyr
Rebecca Brockman
Laura Wihak
Gregory Hansen
Lessons Learned from a Small Pediatric Continuous Renal Replacement Therapy Program
Critical Care Research and Practice
title Lessons Learned from a Small Pediatric Continuous Renal Replacement Therapy Program
title_full Lessons Learned from a Small Pediatric Continuous Renal Replacement Therapy Program
title_fullStr Lessons Learned from a Small Pediatric Continuous Renal Replacement Therapy Program
title_full_unstemmed Lessons Learned from a Small Pediatric Continuous Renal Replacement Therapy Program
title_short Lessons Learned from a Small Pediatric Continuous Renal Replacement Therapy Program
title_sort lessons learned from a small pediatric continuous renal replacement therapy program
url http://dx.doi.org/10.1155/2021/6481559
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