Single‐cell transcriptomics and metabolomic analysis reveal adenosine‐derived metabolites over‐representation in pseudohypoxic neuroendocrine tumours

Single‐cell transcriptomics and metabolomic analysis reveal adenosine‐derived metabolites over‐representation in pseudohypoxic neuroendocrine tumours

Saved in:

Bibliographic Details
Main Authors:	Yuval Kahan Yossef, Liav Sela Peremen, Alona Telerman, Gil Goldinger, Sergey Malitsky, Maxim Itkin, Reut Halperin, Naama Peshes Yaloz, Amit Tirosh
Format:	Article
Language:	English
Published:	Wiley 2025-02-01
Series:	Clinical and Translational Medicine
Online Access:	https://doi.org/10.1002/ctm2.70159
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single-cell RNA sequencing
by: Einav Somech, et al.
Published: (2025-07-01)

Pseudohypoxic stabilization of HIF1α via cyclophilin D suppression promotes melanoma metastasis
by: Hye-Kyung Park, et al.
Published: (2025-07-01)

Pseudohypoxia caused by germline genetic alterations in the VHL gene is associated with increased diabetes and cardiovascular risk: a UK biobank study
by: Reut Halperin, et al.
Published: (2025-06-01)

Integrative transcriptomics and metabolomics reveal neuroendocrine-lipid crosstalk and adenosine signaling in broiler under heat stress
by: Bingxing An, et al.
Published: (2025-07-01)

Adenosine and adenosine receptors: a “double-edged sword” in cardiovascular system
by: Yongqi Qian, et al.
Published: (2025-07-01)

Neuroendocrine Tumours: a Literature Review
by: K. V. Menshikov, et al.
Published: (2021-05-01)

NEUROENDOCRINE TUMOURS OF THE APPENDIX IN CHILDREN AND ADOLESCENTS
by: Neža Salobir, et al.
Published: (2024-12-01)

Urine Metabolomic Profiling and Machine Learning in Autism Spectrum Disorder Diagnosis: Toward Precision Treatment
by: Shula Shazman, et al.
Published: (2025-05-01)

Metformin in the treatment of colorectal cancer and neuroendocrine tumours
by: Karolina Daniłowska, et al.
Published: (2024-08-01)

Adenosine, Energy Metabolism, and Sleep
by: Tarja Porkka-Heiskanen, et al.
Published: (2003-01-01)

An Unusual Location of Neuroendocrine Tumour: Primary Hepatic Origin
by: A. Bahar Ceyran, et al.
Published: (2015-01-01)

Liver metastases in gastroenteropancreatic neuroendocrine tumours – treatment methods
by: Paweł Gut
Published: (2020-01-01)

Unusual Paraneoplastic Syndrome Accompanies Neuroendocrine Tumours of the Pancreas
by: Helga Bertani, et al.
Published: (2011-01-01)

Adenosine Receptors and Wound Healing, Revised
by: Bruce M. Cronstein
Published: (2006-01-01)

Adenosine: A key player in neuroinflammation
by: Qilin Guo, et al.
Published: (2026-04-01)

Feed-Forward Inhibition of CD73 and Upregulation of Adenosine Deaminase Contribute to the Loss of Adenosine Neuromodulation in Postinflammatory Ileitis
by: Cátia Vieira, et al.
Published: (2014-01-01)

Chromatin regulators as capacitors of interspecies variations in gene expression
by: Itay Tirosh, et al.
Published: (2010-11-01)

On the relation between promoter divergence and gene expression evolution
by: Itay Tirosh, et al.
Published: (2008-01-01)

Effects of adenosine and dipyridamole on serum levels of some biochemical markers in rabbits: Running title: Biochemical effects of adenosine and dipyridamole
by: Taghreed Hazem Saber Alfakje, et al.
Published: (2022-12-01)

Efficacy of Adenosine in the Differential Diagnosis of Narrow QRS Complex Tachyarrhythmia: A Case Diagnosed with Atrial Flutter After Adenosine
by: Aziz Zeytin, et al.
Published: (2023-08-01)

A Case of Sinonasal Neuroendocrine Tumour: Diagnostic and Therapuetic Challenge
by: Gundappa Mahajan, et al.
Published: (2025-07-01)

Prognostic Impact of DNA-Image-Cytometry in Neuroendocrine (Carcinoid) Tumours
by: Steffen Hauptmann
Published: (2006-01-01)

Neuroendocrine Tumour as a Diagnostic and Prognostic Criterion for Autoimmune Gastritis
by: S. I. Mozgovoi, et al.
Published: (2020-01-01)

TREATMENT OF PATIENTS WITH PANCREATIC NEUROENDOCRINE TUMOURS DEPENDING ON THE DIFFERENTIATION GRADE
by: A. Z. Isyangulova, et al.
Published: (2019-11-01)

The natural course of cystic pancreatic neuroendocrine tumours in MEN1
by: Eline N M van Vliembergen, et al.
Published: (2025-02-01)

The Role of Uridine Adenosine Tetraphosphate in the Vascular System
by: Takayuki Matsumoto, et al.
Published: (2011-01-01)

Ketogenic diet, adenosine, and dopamine in addiction and psychiatry
by: David N. Ruskin, et al.
Published: (2025-03-01)

New Algorithm of Stress Echocardiography with Adenosine Triphosphate
by: N. Yu. Nelassov, et al.
Published: (2020-11-01)

Adenosine stress protocols for myocardial perfusion imaging
by: Baškot Branislav, et al.
Published: (2008-01-01)

Adenosine Concentration Determination for Tumor Microenvironment Simulation
by: Chun Chen, et al.
Published: (2025-08-01)

N6-adenosine methylation in MiRNAs.
by: Tea Berulava, et al.
Published: (2015-01-01)

The response to adenosine tells all: What is the mechanism?
by: Shu Hirata, et al.
Published: (2024-12-01)

Dynamic changes in serum adenosine and the adenosine metabolism-based signature for prognosis in HER2-positive metastatic breast cancer patients
by: Lijun Wang, et al.
Published: (2024-12-01)

Long Term Survival Analysis of Hepatectomy for Neuroendocrine Tumour Liver Metastases
by: Tan To Cheung, et al.
Published: (2014-01-01)

Unmasking insulinoma following commencement of somatostatin analogues in malignant neuroendocrine tumours
by: Isuru Gamage, et al.
Published: (2025-07-01)

Ileal Neuroendocrine Tumour of Carcinoid Type 1: A Case Report
by: Saurabh Gawand, et al.
Published: (2025-03-01)

The Impact of Preoperative Endoscopic Ultrasound on the Surgical Management of Pancreatic Neuroendocrine Tumours
by: Fahad Alsohaibani, et al.
Published: (2008-01-01)

NET Models Meeting 2024 white paper: the current state of neuroendocrine tumour research models and our future aspirations
by: Po Hien Ear, et al.
Published: (2024-12-01)

The Role of Extracellular Adenosine Generation in the Development of Autoimmune Diseases
by: F. Morandi, et al.
Published: (2018-01-01)

Enabling adenosine signaling to promote aged fracture healing
by: Hunter Newman, et al.
Published: (2025-04-01)