The Prevention of Surgical Site Infection in Elective Colon Surgery

Infections at the surgical site continue to occur in as many as 20% of elective colon resection cases. Methods to reduce these infections are inconsistently applied. Surgical site infection (SSI) is the result of multiple interactive variables including the inoculum of bacteria that contaminate the...

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Main Author: Donald E. Fry
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2013/896297
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author Donald E. Fry
author_facet Donald E. Fry
author_sort Donald E. Fry
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description Infections at the surgical site continue to occur in as many as 20% of elective colon resection cases. Methods to reduce these infections are inconsistently applied. Surgical site infection (SSI) is the result of multiple interactive variables including the inoculum of bacteria that contaminate the site, the virulence of the contaminating microbes, and the local environment at the surgical site. These variables that promote infection are potentially offset by the effectiveness of the host defense. Reduction in the inoculum of bacteria is achieved by appropriate surgical site preparation, systemic preventive antibiotics, and use of mechanical bowel preparation in conjunction with the oral antibiotic bowel preparation. Intraoperative reduction of hematoma, necrotic tissue, foreign bodies, and tissue dead space will reduce infections. Enhancement of the host may be achieved by perioperative supplemental oxygenation, maintenance of normothermia, and glycemic control. These methods require additional research to identify optimum application. Uniform application of currently understood methods and continued research into new methods to reduce microbial contamination and enhancement of host responsiveness can lead to better outcomes.
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spelling doaj-art-ed794df3e7de4f4f8c6ae7d8a4deff952025-08-20T03:21:11ZengWileyScientifica2090-908X2013-01-01201310.1155/2013/896297896297The Prevention of Surgical Site Infection in Elective Colon SurgeryDonald E. Fry0Michael Pine and Associates, 1 East Wacker Drive, No. 1210, Chicago, IL 60601, USAInfections at the surgical site continue to occur in as many as 20% of elective colon resection cases. Methods to reduce these infections are inconsistently applied. Surgical site infection (SSI) is the result of multiple interactive variables including the inoculum of bacteria that contaminate the site, the virulence of the contaminating microbes, and the local environment at the surgical site. These variables that promote infection are potentially offset by the effectiveness of the host defense. Reduction in the inoculum of bacteria is achieved by appropriate surgical site preparation, systemic preventive antibiotics, and use of mechanical bowel preparation in conjunction with the oral antibiotic bowel preparation. Intraoperative reduction of hematoma, necrotic tissue, foreign bodies, and tissue dead space will reduce infections. Enhancement of the host may be achieved by perioperative supplemental oxygenation, maintenance of normothermia, and glycemic control. These methods require additional research to identify optimum application. Uniform application of currently understood methods and continued research into new methods to reduce microbial contamination and enhancement of host responsiveness can lead to better outcomes.http://dx.doi.org/10.1155/2013/896297
spellingShingle Donald E. Fry
The Prevention of Surgical Site Infection in Elective Colon Surgery
Scientifica
title The Prevention of Surgical Site Infection in Elective Colon Surgery
title_full The Prevention of Surgical Site Infection in Elective Colon Surgery
title_fullStr The Prevention of Surgical Site Infection in Elective Colon Surgery
title_full_unstemmed The Prevention of Surgical Site Infection in Elective Colon Surgery
title_short The Prevention of Surgical Site Infection in Elective Colon Surgery
title_sort prevention of surgical site infection in elective colon surgery
url http://dx.doi.org/10.1155/2013/896297
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AT donaldefry preventionofsurgicalsiteinfectioninelectivecolonsurgery