Associated Factors for Erectile Dysfunction Occurrence in Patients with Coronary Artery Disease: A Cross-sectional Study
Background: Erectile dysfunction (ED) is associated with cardiovascular events, and a significant proportion of men with coronary artery disease (CAD) exhibit early signs of ED. Moreover, both of these disorders shared common risk factors in previous studies. This study was conducted to determine wh...
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Shiraz University of Medical Sciences
2025-01-01
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| Series: | Iranian Journal of Medical Sciences |
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| Online Access: | https://ijms.sums.ac.ir/article_50421_51b5bbdd14ff3d0c5f90eca1d761348d.pdf |
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| author | Ali Hamidi Madani Fardin Mirbolouk Mona Naghshbandi Tolou Hasandokht Mahboobe Gholipour Mohammad Sajjad Zabihi Mohammad Hamidi Madani |
| author_facet | Ali Hamidi Madani Fardin Mirbolouk Mona Naghshbandi Tolou Hasandokht Mahboobe Gholipour Mohammad Sajjad Zabihi Mohammad Hamidi Madani |
| author_sort | Ali Hamidi Madani |
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| description | Background: Erectile dysfunction (ED) is associated with cardiovascular events, and a significant proportion of men with coronary artery disease (CAD) exhibit early signs of ED. Moreover, both of these disorders shared common risk factors in previous studies. This study was conducted to determine which risk factors and conditions in CAD patients might contribute to the occurrence of ED.Methods: This analytical cross-sectional study was conducted in the North of Iran from October 2016 to September 2017. 316 patients with coronary artery disease were enrolled. Demographic information were collected using a checklist, and the International Index of Erectile Function (IIEF-15) questionnaire was used to determine the participant’s ED status. Univariate and multivariate logistic regression were used to investigate associated factors.Results: The mean age of the participants was 56.51±9.88 years. About 55.1% of the patients had ED. Moreover, the severity of CAD was independently associated with an increased risk of ED (OR=4.11, 95%CI=1.69-9.97), with patients having more than one involved coronary artery and greater coronary artery stenosis had a higher risk of developing ED occurrence (OR=3.74, 95%CI=1.72-8.09). Besides, age (OR=1.23, 95%CI=1.18-1.29) and BMI (OR=1.26, 95%CI=1.13-1.41) were independent predictors of ED occurrence in CAD patients. Conclusion: Higher CAD severity, older age, and higher BMI were all independent predictors of ED occurrence in CAD patients. While, diabetes mellitus, dyslipidemia, and smoking were not independent risk factors, they could contribute to the development of ED when combined with other risk factors. |
| format | Article |
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| institution | Kabale University |
| issn | 0253-0716 1735-3688 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Shiraz University of Medical Sciences |
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| series | Iranian Journal of Medical Sciences |
| spelling | doaj-art-ed75c279b4ea489f9acf07fb57a96b992025-02-11T07:30:14ZengShiraz University of Medical SciencesIranian Journal of Medical Sciences0253-07161735-36882025-01-01501374310.30476/ijms.2024.100731.331250421Associated Factors for Erectile Dysfunction Occurrence in Patients with Coronary Artery Disease: A Cross-sectional StudyAli Hamidi Madani0Fardin Mirbolouk1Mona Naghshbandi2Tolou Hasandokht3Mahboobe Gholipour4Mohammad Sajjad Zabihi5Mohammad Hamidi Madani6Urology Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranCardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranCardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranCardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranCardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranDepartment of Urology, Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, School of Medicine, Tehran, IranDepartment of Urology, Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, School of Medicine, Tehran, IranBackground: Erectile dysfunction (ED) is associated with cardiovascular events, and a significant proportion of men with coronary artery disease (CAD) exhibit early signs of ED. Moreover, both of these disorders shared common risk factors in previous studies. This study was conducted to determine which risk factors and conditions in CAD patients might contribute to the occurrence of ED.Methods: This analytical cross-sectional study was conducted in the North of Iran from October 2016 to September 2017. 316 patients with coronary artery disease were enrolled. Demographic information were collected using a checklist, and the International Index of Erectile Function (IIEF-15) questionnaire was used to determine the participant’s ED status. Univariate and multivariate logistic regression were used to investigate associated factors.Results: The mean age of the participants was 56.51±9.88 years. About 55.1% of the patients had ED. Moreover, the severity of CAD was independently associated with an increased risk of ED (OR=4.11, 95%CI=1.69-9.97), with patients having more than one involved coronary artery and greater coronary artery stenosis had a higher risk of developing ED occurrence (OR=3.74, 95%CI=1.72-8.09). Besides, age (OR=1.23, 95%CI=1.18-1.29) and BMI (OR=1.26, 95%CI=1.13-1.41) were independent predictors of ED occurrence in CAD patients. Conclusion: Higher CAD severity, older age, and higher BMI were all independent predictors of ED occurrence in CAD patients. While, diabetes mellitus, dyslipidemia, and smoking were not independent risk factors, they could contribute to the development of ED when combined with other risk factors.https://ijms.sums.ac.ir/article_50421_51b5bbdd14ff3d0c5f90eca1d761348d.pdfcoronary artery disease ● erectile dysfunction ● risk factors ● coronary angiography |
| spellingShingle | Ali Hamidi Madani Fardin Mirbolouk Mona Naghshbandi Tolou Hasandokht Mahboobe Gholipour Mohammad Sajjad Zabihi Mohammad Hamidi Madani Associated Factors for Erectile Dysfunction Occurrence in Patients with Coronary Artery Disease: A Cross-sectional Study Iranian Journal of Medical Sciences coronary artery disease ● erectile dysfunction ● risk factors ● coronary angiography |
| title | Associated Factors for Erectile Dysfunction Occurrence in Patients with Coronary Artery Disease: A Cross-sectional Study |
| title_full | Associated Factors for Erectile Dysfunction Occurrence in Patients with Coronary Artery Disease: A Cross-sectional Study |
| title_fullStr | Associated Factors for Erectile Dysfunction Occurrence in Patients with Coronary Artery Disease: A Cross-sectional Study |
| title_full_unstemmed | Associated Factors for Erectile Dysfunction Occurrence in Patients with Coronary Artery Disease: A Cross-sectional Study |
| title_short | Associated Factors for Erectile Dysfunction Occurrence in Patients with Coronary Artery Disease: A Cross-sectional Study |
| title_sort | associated factors for erectile dysfunction occurrence in patients with coronary artery disease a cross sectional study |
| topic | coronary artery disease ● erectile dysfunction ● risk factors ● coronary angiography |
| url | https://ijms.sums.ac.ir/article_50421_51b5bbdd14ff3d0c5f90eca1d761348d.pdf |
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