Pancreatic B-13 Cell Trans-Differentiation to Hepatocytes Is Dependent on Epigenetic-Regulated Changes in Gene Expression.
The proliferative B-13 pancreatic cell line is unique in its ability to generate functional hepatocyte-like (B-13/H) cells in response to exposure to glucocorticoid. In these studies, quantitatively comparable hepatic levels of liver-specific and liver-enriched transcription factor and hepatocyte de...
Saved in:
| Main Authors: | Emma A Fairhall, Michelle A Charles, Philip M E Probert, Karen Wallace, Jennifer Gibb, Chandni Ravindan, Martin Soloman, Matthew C Wright |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2016-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0150959&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Epigenetic Landscape of DNA Methylation in Pancreatic Ductal Adenocarcinoma
by: Peiyi Liu, et al.
Published: (2024-11-01) -
Trans-Reactivation: A New Epigenetic Phenomenon Underlying Transcriptional Reactivation of Silenced Genes.
by: Maria Cristina Onorati, et al.
Published: (2015-08-01) -
SDF-1/CXCR4 Axis Promotes MSCs to Repair Liver Injury Partially through Trans-Differentiation and Fusion with Hepatocytes
by: Ning-Bo Hao, et al.
Published: (2015-01-01) -
Hepatocytic Insufficiency
by: V. I. Reshetnyak
Published: (2005-06-01) -
Hepatocyte reporter cells and integrated metabolomic and transcriptomic analyses reveal insights into hepatocyte changes in offspring of pregnancies with obesity
by: Svetlana Y. Kozlovich, et al.
Published: (2025-07-01)