Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction

Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction

Abstract Background Postoperative cognitive dysfunction (POCD) represents a post-surgical complication that features progressive cognitive impairment and memory loss, often occurring in elderly patients. This study aimed to investigate the potential biological mechanisms underlying POCD. Methods Mal...

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Bibliographic Details
Main Authors: Jingrun Lin, Xiaoqiu Zhu, Xuan Li, Yu Hong, Yaohui Liang, Siqi Chen, Chenzhuo Feng, Lin Cao
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Anesthesiology
Subjects:
POCD
Aging
LncRNA
MiRNA
MRNA
CeRNA
Online Access:https://doi.org/10.1186/s12871-025-02928-z
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