Positron emission tomography–computed tomography-associated incidental neoplasms of the thyroid gland
With the increasing use of 18F-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET-CT) scans in oncology, the finding of thyroid incidentalomas, also popularly described as PET-associated incidental neoplasms (PAINs) of the thyroid gland is not unusual. The 18F-FDG PET-CT...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2020-01-01
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| Series: | World Journal of Nuclear Medicine |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_33_19 |
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| author | K Kamakshi Arvind Krishnamurthy V Karthik Preetha Vinodkumar R Kumar K Lakshmipathy |
| author_facet | K Kamakshi Arvind Krishnamurthy V Karthik Preetha Vinodkumar R Kumar K Lakshmipathy |
| author_sort | K Kamakshi |
| collection | DOAJ |
| description | With the increasing use of 18F-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET-CT) scans in oncology, the finding of thyroid incidentalomas, also popularly described as PET-associated incidental neoplasms (PAINs) of the thyroid gland is not unusual. The 18F-FDG PET-CT scans of all patients who underwent imaging for indications other than thyroid malignancy at our tertiary care center between January 1 and December 31, 2017, were retrospectively reviewed for PAINs of the thyroid. A total of 173718F-FDG PET-CT scans were done at our center in the year 2017. 288 thyroid incidentalomas were detected in the said period; the rate of PET-CT-detected thyroid incidentalomas being 16.58%, focal incidentalomas among them being 11.7%. Only 29 out of 204 patients (14.21%) with focal thyroid incidentalomas in our cohort underwent an aspiration cytology and/or ultrasound. The rate of malignancy among the PET detected focal thyroid incidentalomas in the cohort of patients with a proven diagnosis was 10.34%. Our study highlights the challenges in the evaluation and management of PAIN in a tertiary care oncology setting. None of the factors studied including nodule size and standardized uptake value predicted the risk of malignancy. Clinicians specializing in the management of thyroid nodules need to understand the clinical significance of the PAIN, and we hope that our unique experience adds to the limited clinical information available in this regard. |
| format | Article |
| id | doaj-art-ed62ba10c9374e8bacf168cc79e6597c |
| institution | DOAJ |
| issn | 1450-1147 1607-3312 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
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| series | World Journal of Nuclear Medicine |
| spelling | doaj-art-ed62ba10c9374e8bacf168cc79e6597c2025-08-20T02:54:42ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122020-01-011901364010.4103/wjnm.WJNM_33_19Positron emission tomography–computed tomography-associated incidental neoplasms of the thyroid glandK Kamakshi0Arvind Krishnamurthy1V Karthik2Preetha Vinodkumar3R Kumar4K Lakshmipathy5Department of Surgical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu, IndiaDepartment of Surgical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu, IndiaDepartment of Surgical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu, IndiaDepartment of Clinical Research, Cancer Institute (WIA), Chennai, Tamil Nadu, IndiaDepartment of Nuclear Medicine, Cancer Institute (WIA), Chennai, Tamil Nadu, IndiaHCG PET-CT Centre, Chennai, Tamil NaduWith the increasing use of 18F-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET-CT) scans in oncology, the finding of thyroid incidentalomas, also popularly described as PET-associated incidental neoplasms (PAINs) of the thyroid gland is not unusual. The 18F-FDG PET-CT scans of all patients who underwent imaging for indications other than thyroid malignancy at our tertiary care center between January 1 and December 31, 2017, were retrospectively reviewed for PAINs of the thyroid. A total of 173718F-FDG PET-CT scans were done at our center in the year 2017. 288 thyroid incidentalomas were detected in the said period; the rate of PET-CT-detected thyroid incidentalomas being 16.58%, focal incidentalomas among them being 11.7%. Only 29 out of 204 patients (14.21%) with focal thyroid incidentalomas in our cohort underwent an aspiration cytology and/or ultrasound. The rate of malignancy among the PET detected focal thyroid incidentalomas in the cohort of patients with a proven diagnosis was 10.34%. Our study highlights the challenges in the evaluation and management of PAIN in a tertiary care oncology setting. None of the factors studied including nodule size and standardized uptake value predicted the risk of malignancy. Clinicians specializing in the management of thyroid nodules need to understand the clinical significance of the PAIN, and we hope that our unique experience adds to the limited clinical information available in this regard.http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_33_19positron emission tomographypositron emission tomography associated incidental neoplasmsprognosisthyroid incidentalomas |
| spellingShingle | K Kamakshi Arvind Krishnamurthy V Karthik Preetha Vinodkumar R Kumar K Lakshmipathy Positron emission tomography–computed tomography-associated incidental neoplasms of the thyroid gland World Journal of Nuclear Medicine positron emission tomography positron emission tomography associated incidental neoplasms prognosis thyroid incidentalomas |
| title | Positron emission tomography–computed tomography-associated incidental neoplasms of the thyroid gland |
| title_full | Positron emission tomography–computed tomography-associated incidental neoplasms of the thyroid gland |
| title_fullStr | Positron emission tomography–computed tomography-associated incidental neoplasms of the thyroid gland |
| title_full_unstemmed | Positron emission tomography–computed tomography-associated incidental neoplasms of the thyroid gland |
| title_short | Positron emission tomography–computed tomography-associated incidental neoplasms of the thyroid gland |
| title_sort | positron emission tomography computed tomography associated incidental neoplasms of the thyroid gland |
| topic | positron emission tomography positron emission tomography associated incidental neoplasms prognosis thyroid incidentalomas |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_33_19 |
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