Clinical Presentation and Outcome of Five Neonates With Enterovirus Central Nervous System Infection: Contrasting One Kawasaki-Like Case With Cardiac Involvement and Seizures With Four Benign Cases

Conclusions: In neonates who appear septic without an apparent focus, EV CNS infection should be considered and can be diagnosed by CSF PCR testing. Diagnosis leads to earlier discontinuation of antibiotic treatment and shorter hospital stay. Neonates with EV infection should be screened for cardiac...

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Main Authors: Alina Peternell, Christopher Schödl, Irena Odri Komazec, Matthias Baumann, Christian Lechner
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/crpe/5569829
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author Alina Peternell
Christopher Schödl
Irena Odri Komazec
Matthias Baumann
Christian Lechner
author_facet Alina Peternell
Christopher Schödl
Irena Odri Komazec
Matthias Baumann
Christian Lechner
author_sort Alina Peternell
collection DOAJ
description Conclusions: In neonates who appear septic without an apparent focus, EV CNS infection should be considered and can be diagnosed by CSF PCR testing. Diagnosis leads to earlier discontinuation of antibiotic treatment and shorter hospital stay. Neonates with EV infection should be screened for cardiac complications and in severe cases treated with IVIG. CSF abnormalities might predict a more severe disease course and justify closer monitoring.
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institution Kabale University
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publishDate 2025-01-01
publisher Wiley
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series Case Reports in Pediatrics
spelling doaj-art-ed5c6d35710f4f3f8df7a6db31be10092025-08-20T03:55:59ZengWileyCase Reports in Pediatrics2090-68112025-01-01202510.1155/crpe/5569829Clinical Presentation and Outcome of Five Neonates With Enterovirus Central Nervous System Infection: Contrasting One Kawasaki-Like Case With Cardiac Involvement and Seizures With Four Benign CasesAlina Peternell0Christopher Schödl1Irena Odri Komazec2Matthias Baumann3Christian Lechner4Division of Pediatrics I-Pediatric NeurologyDivision of Pediatrics I-Pediatric NeurologyDivision of Pediatrics III-Cardiology, Pulmonology, Allergology and Cystic FibrosisDivision of Pediatrics I-Pediatric NeurologyDivision of Pediatrics I-Pediatric NeurologyConclusions: In neonates who appear septic without an apparent focus, EV CNS infection should be considered and can be diagnosed by CSF PCR testing. Diagnosis leads to earlier discontinuation of antibiotic treatment and shorter hospital stay. Neonates with EV infection should be screened for cardiac complications and in severe cases treated with IVIG. CSF abnormalities might predict a more severe disease course and justify closer monitoring.http://dx.doi.org/10.1155/crpe/5569829
spellingShingle Alina Peternell
Christopher Schödl
Irena Odri Komazec
Matthias Baumann
Christian Lechner
Clinical Presentation and Outcome of Five Neonates With Enterovirus Central Nervous System Infection: Contrasting One Kawasaki-Like Case With Cardiac Involvement and Seizures With Four Benign Cases
Case Reports in Pediatrics
title Clinical Presentation and Outcome of Five Neonates With Enterovirus Central Nervous System Infection: Contrasting One Kawasaki-Like Case With Cardiac Involvement and Seizures With Four Benign Cases
title_full Clinical Presentation and Outcome of Five Neonates With Enterovirus Central Nervous System Infection: Contrasting One Kawasaki-Like Case With Cardiac Involvement and Seizures With Four Benign Cases
title_fullStr Clinical Presentation and Outcome of Five Neonates With Enterovirus Central Nervous System Infection: Contrasting One Kawasaki-Like Case With Cardiac Involvement and Seizures With Four Benign Cases
title_full_unstemmed Clinical Presentation and Outcome of Five Neonates With Enterovirus Central Nervous System Infection: Contrasting One Kawasaki-Like Case With Cardiac Involvement and Seizures With Four Benign Cases
title_short Clinical Presentation and Outcome of Five Neonates With Enterovirus Central Nervous System Infection: Contrasting One Kawasaki-Like Case With Cardiac Involvement and Seizures With Four Benign Cases
title_sort clinical presentation and outcome of five neonates with enterovirus central nervous system infection contrasting one kawasaki like case with cardiac involvement and seizures with four benign cases
url http://dx.doi.org/10.1155/crpe/5569829
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