Ginsenoside Rh2 regulates triple-negative breast cancer proliferation and apoptosis via the IL-6/JAK2/STAT3 pathway

Ginsenoside Rh2 regulates triple-negative breast cancer proliferation and apoptosis via the IL-6/JAK2/STAT3 pathway

IntroductionTriple-negative breast cancer (TNBC) is the most challenging subtype of breast cancer to treat. While previous studies have demonstrated that ginsenoside Rh2 induces apoptosis in TNBC cells, the specific molecular targets and underlying mechanisms remain poorly understood. This study aim...

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Bibliographic Details
Main Authors: Rumeng Ding, Quancheng Kan, Ting Wang, Ran Xiao, Yanan Song, Duolu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
ginsenoside Rh2
triple-negative breast cancer
network Pharmacology
IL-6/JAK2/STAT3 pathway
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1483896/full
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