Angiotensin Converting Enzyme and Dipeptidyl Peptidase IV Inhibitory Activity of Protein Hydrolysates Obtained from Sunflower Meal
In this study, the potential of sunflower protein hydrolysates to inhibit angiotensin converting enzyme (ACE) and dipeptidyl peptidase-IV (DPP-IV) enzyme was determined. Sunflower protein isolate was hydrolyzed with Alcalase and Trypsin+Chymotrypsin enzymes and the obtained protein hydrolysates were...
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Hasan Eleroğlu
2022-05-01
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| Series: | Turkish Journal of Agriculture: Food Science and Technology |
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| Online Access: | http://www.agrifoodscience.com/index.php/TURJAF/article/view/4959 |
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| author | Şebnem Şimşek |
| author_facet | Şebnem Şimşek |
| author_sort | Şebnem Şimşek |
| collection | DOAJ |
| description | In this study, the potential of sunflower protein hydrolysates to inhibit angiotensin converting enzyme (ACE) and dipeptidyl peptidase-IV (DPP-IV) enzyme was determined. Sunflower protein isolate was hydrolyzed with Alcalase and Trypsin+Chymotrypsin enzymes and the obtained protein hydrolysates were fractionated by ultrafiltration (5 kDa). The degrees of hydrolysis achieved by Alcalase and Trypsin+Chymotrypsin enzymes were 27% and 13%, respectively. The most potent ACE inhibitory activity (IC50=0.06 ± 0.01 mg/mL) was observed for the fraction that has molecular weight below 5 kDa, which was hydrolyzed by Trypsin+Chymotrypsin enzyme (P |
| format | Article |
| id | doaj-art-ed51066c09a84734968d984355ab173e |
| institution | OA Journals |
| issn | 2148-127X |
| language | English |
| publishDate | 2022-05-01 |
| publisher | Hasan Eleroğlu |
| record_format | Article |
| series | Turkish Journal of Agriculture: Food Science and Technology |
| spelling | doaj-art-ed51066c09a84734968d984355ab173e2025-08-20T02:22:10ZengHasan EleroğluTurkish Journal of Agriculture: Food Science and Technology2148-127X2022-05-0110591892410.24925/turjaf.v10i5.918-924.49592480Angiotensin Converting Enzyme and Dipeptidyl Peptidase IV Inhibitory Activity of Protein Hydrolysates Obtained from Sunflower MealŞebnem Şimşek0Department of Food Engineering, Faculty of Engineering, Ege University, 35040 Bornova/IzmirIn this study, the potential of sunflower protein hydrolysates to inhibit angiotensin converting enzyme (ACE) and dipeptidyl peptidase-IV (DPP-IV) enzyme was determined. Sunflower protein isolate was hydrolyzed with Alcalase and Trypsin+Chymotrypsin enzymes and the obtained protein hydrolysates were fractionated by ultrafiltration (5 kDa). The degrees of hydrolysis achieved by Alcalase and Trypsin+Chymotrypsin enzymes were 27% and 13%, respectively. The most potent ACE inhibitory activity (IC50=0.06 ± 0.01 mg/mL) was observed for the fraction that has molecular weight below 5 kDa, which was hydrolyzed by Trypsin+Chymotrypsin enzyme (Phttp://www.agrifoodscience.com/index.php/TURJAF/article/view/4959ayçiçek küspesiade inhibisyon aktivitesidpp-iv inhibisyon aktivitesiprotein hidrolizatıenzimatik hidroliz |
| spellingShingle | Şebnem Şimşek Angiotensin Converting Enzyme and Dipeptidyl Peptidase IV Inhibitory Activity of Protein Hydrolysates Obtained from Sunflower Meal Turkish Journal of Agriculture: Food Science and Technology ayçiçek küspesi ade inhibisyon aktivitesi dpp-iv inhibisyon aktivitesi protein hidrolizatı enzimatik hidroliz |
| title | Angiotensin Converting Enzyme and Dipeptidyl Peptidase IV Inhibitory Activity of Protein Hydrolysates Obtained from Sunflower Meal |
| title_full | Angiotensin Converting Enzyme and Dipeptidyl Peptidase IV Inhibitory Activity of Protein Hydrolysates Obtained from Sunflower Meal |
| title_fullStr | Angiotensin Converting Enzyme and Dipeptidyl Peptidase IV Inhibitory Activity of Protein Hydrolysates Obtained from Sunflower Meal |
| title_full_unstemmed | Angiotensin Converting Enzyme and Dipeptidyl Peptidase IV Inhibitory Activity of Protein Hydrolysates Obtained from Sunflower Meal |
| title_short | Angiotensin Converting Enzyme and Dipeptidyl Peptidase IV Inhibitory Activity of Protein Hydrolysates Obtained from Sunflower Meal |
| title_sort | angiotensin converting enzyme and dipeptidyl peptidase iv inhibitory activity of protein hydrolysates obtained from sunflower meal |
| topic | ayçiçek küspesi ade inhibisyon aktivitesi dpp-iv inhibisyon aktivitesi protein hidrolizatı enzimatik hidroliz |
| url | http://www.agrifoodscience.com/index.php/TURJAF/article/view/4959 |
| work_keys_str_mv | AT sebnemsimsek angiotensinconvertingenzymeanddipeptidylpeptidaseivinhibitoryactivityofproteinhydrolysatesobtainedfromsunflowermeal |