Reversing Morphine Induced Tolerance: Insights Into Cetirizine and Green Tea Extract Efficacy

Reversing Morphine Induced Tolerance: Insights Into Cetirizine and Green Tea Extract Efficacy

Background: The treatment of chronic pain presents a considerable difficulty, particularly due to opioid dependence, which is marked by tolerance and withdrawal symptoms. Opioids primarily target mu (μ) opioid receptors, providing pain relief while also leading to various side effects. This research...

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Main Authors: Tahereh Eteraf-Oskouei, Phd, Adel Mahmoudi Gharehbaba, Phd, Solmaz Asnaashari, Phd, Zahra Fazli, Phd, Bohloul Habibi Asl, Phd
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Therapeutic Research
Subjects:
Cetirizine
Green tea
Morphine
P-glycoprotein
Tolerance
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X25000086
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