Collagen membrane versus platelet rich fibrin membrane in bone graft healing: An experimental study in sheep.
Background and objectives: Guided bone regeneration is a term used to define the use of barrier membranes to promote complete osteogenesis. The aim of study was to histologically com-pare the effect of platelet rich fibrin membrane and resorbable Collagen membrane on bone substitute healing. Method...
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College Of Dentistry Hawler Medical University
2020-12-01
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| Series: | Erbil Dental Journal |
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| Online Access: | https://edj.hmu.edu.krd/index.php/journal/article/view/93 |
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| author | Mahdi O. Abdullah Ahmed A. Hayder |
| author_facet | Mahdi O. Abdullah Ahmed A. Hayder |
| author_sort | Mahdi O. Abdullah |
| collection | DOAJ |
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Background and objectives: Guided bone regeneration is a term used to define the use of barrier membranes to promote complete osteogenesis. The aim of study was to histologically com-pare the effect of platelet rich fibrin membrane and resorbable Collagen membrane on bone substitute healing.
Methods: in this experimental study three sheep’s which their weighted between 60-70 kg were used. After intramuscular sedation and local anesthesia, eighteen defects were created about 8 mm in diameter and 5 mm in depth in the lower border of mandible. Six defects on each animal which three in right side and three in left side of the mandible. The defects were filled with Biphasic calcium phosphate bone substitute. The first defect was covered by platelet rich fibrin membrane, the second one covered by Collagen membrane, and third one was left uncovered. The animals were sacrificed at 2, 6, and 12 weeks.
Results: The healing of the grafted defects was histologically studied in all groups, and there was non-significant difference between PRF membrane and collagen membrane in healing of bone substitute at 2, 6, and 12 weeks.There was significant deference between PRF membrane and collagen membrane at 6 week regarding scaffold replacement with mature bone.
Conclusion: The use of PRF membrane shows a good outcome as a low cost biological material capable of improving bone healing defects, grafted with bone substitute.
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| format | Article |
| id | doaj-art-ed3de5341e18403fa77ad257f0fc792d |
| institution | Kabale University |
| issn | 2523-6172 2616-4795 |
| language | English |
| publishDate | 2020-12-01 |
| publisher | College Of Dentistry Hawler Medical University |
| record_format | Article |
| series | Erbil Dental Journal |
| spelling | doaj-art-ed3de5341e18403fa77ad257f0fc792d2025-02-10T20:48:44ZengCollege Of Dentistry Hawler Medical UniversityErbil Dental Journal2523-61722616-47952020-12-0132Collagen membrane versus platelet rich fibrin membrane in bone graft healing: An experimental study in sheep.Mahdi O. Abdullah0Ahmed A. Hayder1Department of Oral and Maxillofacial Surgery, College of Dentistry, Hawler Medical UniversityDepartment of Oral and Maxillofacial Surgery, College of Dentistry, Hawler Medical University Background and objectives: Guided bone regeneration is a term used to define the use of barrier membranes to promote complete osteogenesis. The aim of study was to histologically com-pare the effect of platelet rich fibrin membrane and resorbable Collagen membrane on bone substitute healing. Methods: in this experimental study three sheep’s which their weighted between 60-70 kg were used. After intramuscular sedation and local anesthesia, eighteen defects were created about 8 mm in diameter and 5 mm in depth in the lower border of mandible. Six defects on each animal which three in right side and three in left side of the mandible. The defects were filled with Biphasic calcium phosphate bone substitute. The first defect was covered by platelet rich fibrin membrane, the second one covered by Collagen membrane, and third one was left uncovered. The animals were sacrificed at 2, 6, and 12 weeks. Results: The healing of the grafted defects was histologically studied in all groups, and there was non-significant difference between PRF membrane and collagen membrane in healing of bone substitute at 2, 6, and 12 weeks.There was significant deference between PRF membrane and collagen membrane at 6 week regarding scaffold replacement with mature bone. Conclusion: The use of PRF membrane shows a good outcome as a low cost biological material capable of improving bone healing defects, grafted with bone substitute. https://edj.hmu.edu.krd/index.php/journal/article/view/93Platelet rich fibrin membraneCollagen membraneBone graftBone healing |
| spellingShingle | Mahdi O. Abdullah Ahmed A. Hayder Collagen membrane versus platelet rich fibrin membrane in bone graft healing: An experimental study in sheep. Erbil Dental Journal Platelet rich fibrin membrane Collagen membrane Bone graft Bone healing |
| title | Collagen membrane versus platelet rich fibrin membrane in bone graft healing: An experimental study in sheep. |
| title_full | Collagen membrane versus platelet rich fibrin membrane in bone graft healing: An experimental study in sheep. |
| title_fullStr | Collagen membrane versus platelet rich fibrin membrane in bone graft healing: An experimental study in sheep. |
| title_full_unstemmed | Collagen membrane versus platelet rich fibrin membrane in bone graft healing: An experimental study in sheep. |
| title_short | Collagen membrane versus platelet rich fibrin membrane in bone graft healing: An experimental study in sheep. |
| title_sort | collagen membrane versus platelet rich fibrin membrane in bone graft healing an experimental study in sheep |
| topic | Platelet rich fibrin membrane Collagen membrane Bone graft Bone healing |
| url | https://edj.hmu.edu.krd/index.php/journal/article/view/93 |
| work_keys_str_mv | AT mahdioabdullah collagenmembraneversusplateletrichfibrinmembraneinbonegrafthealinganexperimentalstudyinsheep AT ahmedahayder collagenmembraneversusplateletrichfibrinmembraneinbonegrafthealinganexperimentalstudyinsheep |