Exploration of Newer Possibilities to the Synthesis of Diazepine and Quinoline Carboxylic Acid Derivatives

Heterocyclic systems containing benzothiazoles, carbazole (and azacarbazole) moieties have attracted the attention of chemists owing to these nuclei having been identified in the literature as most promising pharmacophores in drug design and synthesis. Based on these observations, it could be antici...

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Main Authors: Vatsala Soni, Meenakshi Sharma, Anshu Agarwal, Dharma Kishore
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2013/149270
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author Vatsala Soni
Meenakshi Sharma
Anshu Agarwal
Dharma Kishore
author_facet Vatsala Soni
Meenakshi Sharma
Anshu Agarwal
Dharma Kishore
author_sort Vatsala Soni
collection DOAJ
description Heterocyclic systems containing benzothiazoles, carbazole (and azacarbazole) moieties have attracted the attention of chemists owing to these nuclei having been identified in the literature as most promising pharmacophores in drug design and synthesis. Based on these observations, it could be anticipated that incorporation of the bioactive azepine moiety and quinoline moiety into the molecular framework of benzothiazoles fused to carbazole (and azacarbazoles) could produce interesting series of compounds 9–12 with enhanced biological activities, whose structure was unequivocally established from its microanalyses and spectral data.
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spelling doaj-art-ed399ae36c5b41dbb1e9ba0b26f8ecf12025-08-20T02:22:09ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/149270149270Exploration of Newer Possibilities to the Synthesis of Diazepine and Quinoline Carboxylic Acid DerivativesVatsala Soni0Meenakshi Sharma1Anshu Agarwal2Dharma Kishore3Department of Chemistry, Banasthali University, Banasthali, Jaipur 304022, IndiaDepartment of Chemistry, Banasthali University, Banasthali, Jaipur 304022, IndiaDepartment of Chemistry, Banasthali University, Banasthali, Jaipur 304022, IndiaDepartment of Chemistry, Banasthali University, Banasthali, Jaipur 304022, IndiaHeterocyclic systems containing benzothiazoles, carbazole (and azacarbazole) moieties have attracted the attention of chemists owing to these nuclei having been identified in the literature as most promising pharmacophores in drug design and synthesis. Based on these observations, it could be anticipated that incorporation of the bioactive azepine moiety and quinoline moiety into the molecular framework of benzothiazoles fused to carbazole (and azacarbazoles) could produce interesting series of compounds 9–12 with enhanced biological activities, whose structure was unequivocally established from its microanalyses and spectral data.http://dx.doi.org/10.1155/2013/149270
spellingShingle Vatsala Soni
Meenakshi Sharma
Anshu Agarwal
Dharma Kishore
Exploration of Newer Possibilities to the Synthesis of Diazepine and Quinoline Carboxylic Acid Derivatives
Journal of Chemistry
title Exploration of Newer Possibilities to the Synthesis of Diazepine and Quinoline Carboxylic Acid Derivatives
title_full Exploration of Newer Possibilities to the Synthesis of Diazepine and Quinoline Carboxylic Acid Derivatives
title_fullStr Exploration of Newer Possibilities to the Synthesis of Diazepine and Quinoline Carboxylic Acid Derivatives
title_full_unstemmed Exploration of Newer Possibilities to the Synthesis of Diazepine and Quinoline Carboxylic Acid Derivatives
title_short Exploration of Newer Possibilities to the Synthesis of Diazepine and Quinoline Carboxylic Acid Derivatives
title_sort exploration of newer possibilities to the synthesis of diazepine and quinoline carboxylic acid derivatives
url http://dx.doi.org/10.1155/2013/149270
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AT anshuagarwal explorationofnewerpossibilitiestothesynthesisofdiazepineandquinolinecarboxylicacidderivatives
AT dharmakishore explorationofnewerpossibilitiestothesynthesisofdiazepineandquinolinecarboxylicacidderivatives