Rapamycin Augments the NMDA-Mediated TNF Suppression of MRSA-Stimulated RAW264.7 Murine Macrophages

Rapamycin Augments the NMDA-Mediated TNF Suppression of MRSA-Stimulated RAW264.7 Murine Macrophages

Background. Methicillin-resistant Staphylococcus aureus (MRSA) can stimulate massive cytokine release. Ketamine suppresses tumor necrosis factor (TNF) secretion by MRSA-stimulated RAW264.7 macrophages, and the mechanism likely involves N-methyl-D-aspartic acid (NMDA) receptor antagonism. The downstr...

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Bibliographic Details
Main Authors: Thomas Spentzas, Rebekah K. H. Shappley, Fabio Savorgnan, Elizabeth Meals, B. Keith English
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2012/542727
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