Inescapable Fibrosis: The Development of Desquamative Interstitial Pneumonia Post-Lung Transplantation Performed for a Patient with Idiopathic Pulmonary Fibrosis

Interstitial lung disease is characterised by a combination of cellular proliferation, inflammation of the interstitium and fibrosis within the alveolar wall. A 58-year-old man was referred for lung transplantation after developing worsening dyspnoea and progressive hypoxaemic respiratory failure fr...

Full description

Saved in:
Bibliographic Details
Main Authors: Paul Lilburn, Divya Pillutla, Vanathi Sivasubramaniam, Marshall Plit
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2023/1737309
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849690807988125696
author Paul Lilburn
Divya Pillutla
Vanathi Sivasubramaniam
Marshall Plit
author_facet Paul Lilburn
Divya Pillutla
Vanathi Sivasubramaniam
Marshall Plit
author_sort Paul Lilburn
collection DOAJ
description Interstitial lung disease is characterised by a combination of cellular proliferation, inflammation of the interstitium and fibrosis within the alveolar wall. A 58-year-old man was referred for lung transplantation after developing worsening dyspnoea and progressive hypoxaemic respiratory failure from idiopathic pulmonary fibrosis. Three years later, he developed desquamative interstitial pneumonia in his transplanted lungs, and despite augmentation of immune suppression, he had a progressive decline in his lung function and exercise capacity. Interestingly, in our case, the histopathology obtained post transplant strongly goes against the recurrence of usual interstitial pneumonia/idiopathic pulmonary fibrosis; rather, two separate interstitial disease processes have been identified.
format Article
id doaj-art-ed3287f673bd4bfda80d6a19332cacff
institution DOAJ
issn 2090-6951
language English
publishDate 2023-01-01
publisher Wiley
record_format Article
series Case Reports in Transplantation
spelling doaj-art-ed3287f673bd4bfda80d6a19332cacff2025-08-20T03:21:12ZengWileyCase Reports in Transplantation2090-69512023-01-01202310.1155/2023/1737309Inescapable Fibrosis: The Development of Desquamative Interstitial Pneumonia Post-Lung Transplantation Performed for a Patient with Idiopathic Pulmonary FibrosisPaul Lilburn0Divya Pillutla1Vanathi Sivasubramaniam2Marshall Plit3University of New South WalesSt. Vincent’s HospitalUniversity of New South WalesUniversity of New South WalesInterstitial lung disease is characterised by a combination of cellular proliferation, inflammation of the interstitium and fibrosis within the alveolar wall. A 58-year-old man was referred for lung transplantation after developing worsening dyspnoea and progressive hypoxaemic respiratory failure from idiopathic pulmonary fibrosis. Three years later, he developed desquamative interstitial pneumonia in his transplanted lungs, and despite augmentation of immune suppression, he had a progressive decline in his lung function and exercise capacity. Interestingly, in our case, the histopathology obtained post transplant strongly goes against the recurrence of usual interstitial pneumonia/idiopathic pulmonary fibrosis; rather, two separate interstitial disease processes have been identified.http://dx.doi.org/10.1155/2023/1737309
spellingShingle Paul Lilburn
Divya Pillutla
Vanathi Sivasubramaniam
Marshall Plit
Inescapable Fibrosis: The Development of Desquamative Interstitial Pneumonia Post-Lung Transplantation Performed for a Patient with Idiopathic Pulmonary Fibrosis
Case Reports in Transplantation
title Inescapable Fibrosis: The Development of Desquamative Interstitial Pneumonia Post-Lung Transplantation Performed for a Patient with Idiopathic Pulmonary Fibrosis
title_full Inescapable Fibrosis: The Development of Desquamative Interstitial Pneumonia Post-Lung Transplantation Performed for a Patient with Idiopathic Pulmonary Fibrosis
title_fullStr Inescapable Fibrosis: The Development of Desquamative Interstitial Pneumonia Post-Lung Transplantation Performed for a Patient with Idiopathic Pulmonary Fibrosis
title_full_unstemmed Inescapable Fibrosis: The Development of Desquamative Interstitial Pneumonia Post-Lung Transplantation Performed for a Patient with Idiopathic Pulmonary Fibrosis
title_short Inescapable Fibrosis: The Development of Desquamative Interstitial Pneumonia Post-Lung Transplantation Performed for a Patient with Idiopathic Pulmonary Fibrosis
title_sort inescapable fibrosis the development of desquamative interstitial pneumonia post lung transplantation performed for a patient with idiopathic pulmonary fibrosis
url http://dx.doi.org/10.1155/2023/1737309
work_keys_str_mv AT paullilburn inescapablefibrosisthedevelopmentofdesquamativeinterstitialpneumoniapostlungtransplantationperformedforapatientwithidiopathicpulmonaryfibrosis
AT divyapillutla inescapablefibrosisthedevelopmentofdesquamativeinterstitialpneumoniapostlungtransplantationperformedforapatientwithidiopathicpulmonaryfibrosis
AT vanathisivasubramaniam inescapablefibrosisthedevelopmentofdesquamativeinterstitialpneumoniapostlungtransplantationperformedforapatientwithidiopathicpulmonaryfibrosis
AT marshallplit inescapablefibrosisthedevelopmentofdesquamativeinterstitialpneumoniapostlungtransplantationperformedforapatientwithidiopathicpulmonaryfibrosis