New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature

Prolactinomas are the commonest pituitary adenomas and the major pathological cause of hyperprolactinaemia. Symptomatic prolactinomas are treated mainly by dopamine agonists; surgery and radiotherapy are options for nonresponders. Schizophrenia treatment is based on antipsychotics, which acts mainl...

Full description

Saved in:
Bibliographic Details
Main Authors: Elvis Henrique Santos Andrade, Pedro Mario Pan, Paula F. Ramalho da Silva, Ary Gadelha
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2010/573252
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832545612213518336
author Elvis Henrique Santos Andrade
Pedro Mario Pan
Paula F. Ramalho da Silva
Ary Gadelha
author_facet Elvis Henrique Santos Andrade
Pedro Mario Pan
Paula F. Ramalho da Silva
Ary Gadelha
author_sort Elvis Henrique Santos Andrade
collection DOAJ
description Prolactinomas are the commonest pituitary adenomas and the major pathological cause of hyperprolactinaemia. Symptomatic prolactinomas are treated mainly by dopamine agonists; surgery and radiotherapy are options for nonresponders. Schizophrenia treatment is based on antipsychotics, which acts mainly at serotonergic and dopaminergic systems. We report a case of a 39-year-old schizophrenic male patient that was diagnosed with a macroprolactinoma 8 years after his first psychotic episode. The association of Schizophrenia and prolactinoma represents a clinical challenge once the treatment of one disease can exacerbate the symptoms of the other.
format Article
id doaj-art-ed31af5d279f4d509cd72b536191f14b
institution Kabale University
issn 1687-9627
1687-9635
language English
publishDate 2010-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-ed31af5d279f4d509cd72b536191f14b2025-02-03T07:25:26ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/573252573252New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the LiteratureElvis Henrique Santos Andrade0Pedro Mario Pan1Paula F. Ramalho da Silva2Ary Gadelha3Psychiatry Department, Federal University of São Paulo (UNIFESP), 04023-900 São Paulo , BrazilPsychiatry Department, Federal University of São Paulo (UNIFESP), 04023-900 São Paulo , BrazilPsychiatry Department, Federal University of São Paulo (UNIFESP), 04023-900 São Paulo , BrazilPsychiatry Department, Federal University of São Paulo (UNIFESP), 04023-900 São Paulo , BrazilProlactinomas are the commonest pituitary adenomas and the major pathological cause of hyperprolactinaemia. Symptomatic prolactinomas are treated mainly by dopamine agonists; surgery and radiotherapy are options for nonresponders. Schizophrenia treatment is based on antipsychotics, which acts mainly at serotonergic and dopaminergic systems. We report a case of a 39-year-old schizophrenic male patient that was diagnosed with a macroprolactinoma 8 years after his first psychotic episode. The association of Schizophrenia and prolactinoma represents a clinical challenge once the treatment of one disease can exacerbate the symptoms of the other.http://dx.doi.org/10.1155/2010/573252
spellingShingle Elvis Henrique Santos Andrade
Pedro Mario Pan
Paula F. Ramalho da Silva
Ary Gadelha
New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
Case Reports in Medicine
title New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
title_full New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
title_fullStr New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
title_full_unstemmed New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
title_short New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
title_sort new insights in the management of antipsychotics in the treatment of schizophrenia in a patient with prolactinoma a case report and review of the literature
url http://dx.doi.org/10.1155/2010/573252
work_keys_str_mv AT elvishenriquesantosandrade newinsightsinthemanagementofantipsychoticsinthetreatmentofschizophreniainapatientwithprolactinomaacasereportandreviewoftheliterature
AT pedromariopan newinsightsinthemanagementofantipsychoticsinthetreatmentofschizophreniainapatientwithprolactinomaacasereportandreviewoftheliterature
AT paulaframalhodasilva newinsightsinthemanagementofantipsychoticsinthetreatmentofschizophreniainapatientwithprolactinomaacasereportandreviewoftheliterature
AT arygadelha newinsightsinthemanagementofantipsychoticsinthetreatmentofschizophreniainapatientwithprolactinomaacasereportandreviewoftheliterature