Spatial transcriptomics combined with single-nucleus RNA sequencing reveals glial cell heterogeneity in the human spinal cord

Spatial transcriptomics combined with single-nucleus RNA sequencing reveals glial cell heterogeneity in the human spinal cord

Glial cells play crucial roles in regulating physiological and pathological functions, including sensation, the response to infection and acute injury, and chronic neurodegenerative disorders. Glial cells include astrocytes, microglia, and oligodendrocytes in the central nervous system, and satellit...

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Bibliographic Details
Main Authors: Yali Chen, Yiyong Wei, Jin Liu, Tao Zhu, Cheng Zhou, Donghang Zhang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-11-01
Series:Neural Regeneration Research
Subjects:
astrocyte
glial cell
human
microglia
oligodendrocyte
sex differentiation
single-nucleus rna sequencing
spatial transcriptomics
species variation
spinal cord
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-23-01876
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