Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign

The most common cancer in men is prostate cancer. The Cheerio sign is the computed tomography finding of multiple pulmonary nodules with central lucency resembling the ring-shaped Cheerio breakfast cereal. Unlike bone metastasis, pulmonary involvement is less common. The Cheerio sign has malignant a...

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Main Authors: Creticus Marak, Achuta Kumar Guddati, Adrita Ashraf, James Smith, Prashant Kaushik
Format: Article
Language:English
Published: American College of Physicians 2022-11-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2022.0508
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author Creticus Marak
Achuta Kumar Guddati
Adrita Ashraf
James Smith
Prashant Kaushik
author_facet Creticus Marak
Achuta Kumar Guddati
Adrita Ashraf
James Smith
Prashant Kaushik
author_sort Creticus Marak
collection DOAJ
description The most common cancer in men is prostate cancer. The Cheerio sign is the computed tomography finding of multiple pulmonary nodules with central lucency resembling the ring-shaped Cheerio breakfast cereal. Unlike bone metastasis, pulmonary involvement is less common. The Cheerio sign has malignant and benign etiologies. Thyroid transcription factor-1 (TTF-1) stain is commonly used in the diagnosis of primary lung cancer. TTF-1 positivity in cancers of prostate origin is rare, with only case reports and small case series available in the literature. Metastatic prostate cancer presenting with a Cheerio sign has not been reported in the literature.
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institution OA Journals
issn 2767-7664
language English
publishDate 2022-11-01
publisher American College of Physicians
record_format Article
series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-ed28e28d4c0b4ad0a34f6122aa047c0a2025-08-20T02:11:46ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642022-11-011910.7326/aimcc.2022.0508Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio SignCreticus Marak0Achuta Kumar Guddati1Adrita Ashraf2James Smith3Prashant Kaushik41Department of Medicine, Pulmonary and Critical Care, Northeastern Health System, Tahlequah, Oklahoma2Division of Hematology/Oncology, Augusta University, Augusta, Georgia3Department of Internal Medicine, Northeastern Health System, Tahlequah, Oklahoma4Division of Surgical Oncology, Northeastern Health System, Tahlequah, Oklahoma5Department of Medicine, Rheumatology, Northeastern Health System, Tahlequah, OklahomaThe most common cancer in men is prostate cancer. The Cheerio sign is the computed tomography finding of multiple pulmonary nodules with central lucency resembling the ring-shaped Cheerio breakfast cereal. Unlike bone metastasis, pulmonary involvement is less common. The Cheerio sign has malignant and benign etiologies. Thyroid transcription factor-1 (TTF-1) stain is commonly used in the diagnosis of primary lung cancer. TTF-1 positivity in cancers of prostate origin is rare, with only case reports and small case series available in the literature. Metastatic prostate cancer presenting with a Cheerio sign has not been reported in the literature.https://www.acpjournals.org/doi/10.7326/aimcc.2022.0508
spellingShingle Creticus Marak
Achuta Kumar Guddati
Adrita Ashraf
James Smith
Prashant Kaushik
Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign
Annals of Internal Medicine: Clinical Cases
title Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign
title_full Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign
title_fullStr Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign
title_full_unstemmed Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign
title_short Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign
title_sort prostate adenocarcinoma with atypical immunohistochemistry presenting with a cheerio sign
url https://www.acpjournals.org/doi/10.7326/aimcc.2022.0508
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AT achutakumarguddati prostateadenocarcinomawithatypicalimmunohistochemistrypresentingwithacheeriosign
AT adritaashraf prostateadenocarcinomawithatypicalimmunohistochemistrypresentingwithacheeriosign
AT jamessmith prostateadenocarcinomawithatypicalimmunohistochemistrypresentingwithacheeriosign
AT prashantkaushik prostateadenocarcinomawithatypicalimmunohistochemistrypresentingwithacheeriosign