Chemogenetic tools for modulation of spatial learning in dopamine transporter deficient rats

Chemogenetic tools for modulation of spatial learning in dopamine transporter deficient rats

ObjectivesWe used the chemogenetic tools for the activation of norepinephrine (NE) release in the prefrontal cortex (PFC) of dopamine transporter knockout (DAT-KO) rats. The objective of this study was to evaluate the effect of chemogenetic activation of NE release in the PFC on the performance of a...

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Bibliographic Details
Main Authors: Arina A. Gromova, Taisiia S. Shemiakova, Mikhail G. Khotin, Evgeniia N. Petrunina, Anastasia D. Belskaya, Raul R. Gainetdinov, Natalia P. Kurzina, Anna B. Volnova
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Neuroscience
Subjects:
hyperdopaminergia
dopamine transporter
knockout rats
chemogenetic
learning
Hebb-Williams maze
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1615208/full
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