Establishment of primary cell cultures from canine mammary gland malignant tumours: a preliminary study
Canine mammary gland cancer (CMGC) is the most common neoplastic condition in bitches and is often fatal. There are limited treatment options for CMGC. Primary cell cultures from mammary tumours are promising preclinical in vitro models in which to study personalised treatment approaches. This preli...
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| Format: | Article |
| Language: | English |
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Sciendo
2025-03-01
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| Series: | Journal of Veterinary Research |
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| Online Access: | https://doi.org/10.2478/jvetres-2025-0007 |
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| author | Petrouškova Patŕicia Hudáková Nikola Almášiová Viera Valenčáková Alexandra Horňáková L’ubica Huniadi Mykhailo Čížková Daša |
| author_facet | Petrouškova Patŕicia Hudáková Nikola Almášiová Viera Valenčáková Alexandra Horňáková L’ubica Huniadi Mykhailo Čížková Daša |
| author_sort | Petrouškova Patŕicia |
| collection | DOAJ |
| description | Canine mammary gland cancer (CMGC) is the most common neoplastic condition in bitches and is often fatal. There are limited treatment options for CMGC. Primary cell cultures from mammary tumours are promising preclinical in vitro models in which to study personalised treatment approaches. This preliminary study aimed to establish primary cell cultures from two canine mammary gland neoplasms: a common solid adenocarcinoma and a rare carcinosarcoma. |
| format | Article |
| id | doaj-art-ed183abcc0894839a9eddd80bcb4cea4 |
| institution | OA Journals |
| issn | 2450-8608 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Journal of Veterinary Research |
| spelling | doaj-art-ed183abcc0894839a9eddd80bcb4cea42025-08-20T02:28:05ZengSciendoJournal of Veterinary Research2450-86082025-03-0169115916810.2478/jvetres-2025-0007Establishment of primary cell cultures from canine mammary gland malignant tumours: a preliminary studyPetrouškova Patŕicia0Hudáková Nikola1Almášiová Viera2Valenčáková Alexandra3Horňáková L’ubica4Huniadi Mykhailo5Čížková Daša6Department of Epizootiology, Parasitology and Protection of One Health, University of Veterinary Medicine and Pharmacy in Košice, 041 81Košice, Slovak RepublicSmall Animal Clinic, University Veterinary Hospital, University of Veterinary Medicine and Pharmacy in Košice, 041 81Košice, Slovak RepublicDepartment of Morphological Disciplines, University of Veterinary Medicine and Pharmacy in Košice, 041 81Košice, Slovak RepublicSmall Animal Clinic, University Veterinary Hospital, University of Veterinary Medicine and Pharmacy in Košice, 041 81Košice, Slovak RepublicSmall Animal Clinic, University Veterinary Hospital, University of Veterinary Medicine and Pharmacy in Košice, 041 81Košice, Slovak RepublicSmall Animal Clinic, University Veterinary Hospital, University of Veterinary Medicine and Pharmacy in Košice, 041 81Košice, Slovak RepublicSmall Animal Clinic, University Veterinary Hospital, University of Veterinary Medicine and Pharmacy in Košice, 041 81Košice, Slovak RepublicCanine mammary gland cancer (CMGC) is the most common neoplastic condition in bitches and is often fatal. There are limited treatment options for CMGC. Primary cell cultures from mammary tumours are promising preclinical in vitro models in which to study personalised treatment approaches. This preliminary study aimed to establish primary cell cultures from two canine mammary gland neoplasms: a common solid adenocarcinoma and a rare carcinosarcoma.https://doi.org/10.2478/jvetres-2025-0007canine mammary gland tumourprimary cell culturemuc1ck8/18ki-67 |
| spellingShingle | Petrouškova Patŕicia Hudáková Nikola Almášiová Viera Valenčáková Alexandra Horňáková L’ubica Huniadi Mykhailo Čížková Daša Establishment of primary cell cultures from canine mammary gland malignant tumours: a preliminary study Journal of Veterinary Research canine mammary gland tumour primary cell culture muc1 ck8/18 ki-67 |
| title | Establishment of primary cell cultures from canine mammary gland malignant tumours: a preliminary study |
| title_full | Establishment of primary cell cultures from canine mammary gland malignant tumours: a preliminary study |
| title_fullStr | Establishment of primary cell cultures from canine mammary gland malignant tumours: a preliminary study |
| title_full_unstemmed | Establishment of primary cell cultures from canine mammary gland malignant tumours: a preliminary study |
| title_short | Establishment of primary cell cultures from canine mammary gland malignant tumours: a preliminary study |
| title_sort | establishment of primary cell cultures from canine mammary gland malignant tumours a preliminary study |
| topic | canine mammary gland tumour primary cell culture muc1 ck8/18 ki-67 |
| url | https://doi.org/10.2478/jvetres-2025-0007 |
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