A landscape of X-inactivation during human T cell development

A landscape of X-inactivation during human T cell development

Abstract Females exhibit a more robust immune response to both self-antigens and non-self-antigens than males, resulting in a higher prevalence of autoimmune diseases but more effective responses against infection. Increased expression of X-linked immune genes in female T cells is thought to underli...

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Main Authors: Björn Gylemo, Maike Bensberg, Viktoria Hennings, Christina Lundqvist, Alessandro Camponeschi, Dóra Goldmann, Huan Zhang, Aida Selimović-Pašić, Antonio Lentini, Olov Ekwall, Colm E. Nestor
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54110-7
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