Sickle Cell Disease Activates Peripheral Blood Mononuclear Cells to Induce Cathepsins K and V Activity in Endothelial Cells
Sickle cell disease is a genetic disease that increases systemic inflammation as well as the risk of pediatric strokes, but links between sickle-induced inflammation and arterial remodeling are not clear. Cathepsins are powerful elastases and collagenases secreted by endothelial cells and monocyte-d...
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Main Authors: | Philip M. Keegan, Sindhuja Surapaneni, Manu O. Platt |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | Anemia |
Online Access: | http://dx.doi.org/10.1155/2012/201781 |
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