Prevention and control of avian influenza virus: Recent advances in diagnostic technologies and surveillance strategies

The natural host for avian influenza virus (AIV) is waterfowl. However, certain subtypes have breached species barriers, causing epizootics in many avian and mammalian species with occasional zoonotic infections in humans. The ongoing spread of highly pathogenic avian influenza (HPAI) A(H5N1) poses...

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Main Authors: Qian Niu, Zhiwen Jiang, Lifang Wang, Xiang Ji, Guy Baele, Ying Qin, Liyan Lin, Alexander Lai, Ye Chen, Michael Veit, Shuo Su
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58882-4
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author Qian Niu
Zhiwen Jiang
Lifang Wang
Xiang Ji
Guy Baele
Ying Qin
Liyan Lin
Alexander Lai
Ye Chen
Michael Veit
Shuo Su
author_facet Qian Niu
Zhiwen Jiang
Lifang Wang
Xiang Ji
Guy Baele
Ying Qin
Liyan Lin
Alexander Lai
Ye Chen
Michael Veit
Shuo Su
author_sort Qian Niu
collection DOAJ
description The natural host for avian influenza virus (AIV) is waterfowl. However, certain subtypes have breached species barriers, causing epizootics in many avian and mammalian species with occasional zoonotic infections in humans. The ongoing spread of highly pathogenic avian influenza (HPAI) A(H5N1) poses a significant and growing public health threat. Here, we discuss recent advances in viral detection and characterization technologies and their integration into the diagnostics and surveillance of AIV within a “One Health” framework.
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series Nature Communications
spelling doaj-art-ed0f8587f7294f6aae3396023ef91cb72025-08-20T02:17:52ZengNature PortfolioNature Communications2041-17232025-04-011611710.1038/s41467-025-58882-4Prevention and control of avian influenza virus: Recent advances in diagnostic technologies and surveillance strategiesQian Niu0Zhiwen Jiang1Lifang Wang2Xiang Ji3Guy Baele4Ying Qin5Liyan Lin6Alexander Lai7Ye Chen8Michael Veit9Shuo Su10Department of Laboratory Medicine/Clinical Laboratory Medicine Research Center, West China Hospital, Sichuan UniversityEngineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine, Academy for Advanced Interdisciplinary Studies, Nanjing Agricultural UniversityNational Key Laboratory of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural UniversityDepartment of Mathematics, School of Science and Engineering, Tulane UniversityDepartment of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory for Clinical and Epidemiological Virology, KU LeuvenEngineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine, Academy for Advanced Interdisciplinary Studies, Nanjing Agricultural UniversityDepartment of Laboratory Medicine/Clinical Laboratory Medicine Research Center, West China Hospital, Sichuan UniversityDepartment of Biological and Physical Sciences, College of Agriculture, Health, and Natural Resources, Kentucky State UniversityKey Laboratory of Fujian-Taiwan Animal Pathogen Biology, College of Animal Sciences, Fujian Agriculture and Forestry UniversityInstitute for Virology, Veterinary Faculty, Free University BerlinEngineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine, Academy for Advanced Interdisciplinary Studies, Nanjing Agricultural UniversityThe natural host for avian influenza virus (AIV) is waterfowl. However, certain subtypes have breached species barriers, causing epizootics in many avian and mammalian species with occasional zoonotic infections in humans. The ongoing spread of highly pathogenic avian influenza (HPAI) A(H5N1) poses a significant and growing public health threat. Here, we discuss recent advances in viral detection and characterization technologies and their integration into the diagnostics and surveillance of AIV within a “One Health” framework.https://doi.org/10.1038/s41467-025-58882-4
spellingShingle Qian Niu
Zhiwen Jiang
Lifang Wang
Xiang Ji
Guy Baele
Ying Qin
Liyan Lin
Alexander Lai
Ye Chen
Michael Veit
Shuo Su
Prevention and control of avian influenza virus: Recent advances in diagnostic technologies and surveillance strategies
Nature Communications
title Prevention and control of avian influenza virus: Recent advances in diagnostic technologies and surveillance strategies
title_full Prevention and control of avian influenza virus: Recent advances in diagnostic technologies and surveillance strategies
title_fullStr Prevention and control of avian influenza virus: Recent advances in diagnostic technologies and surveillance strategies
title_full_unstemmed Prevention and control of avian influenza virus: Recent advances in diagnostic technologies and surveillance strategies
title_short Prevention and control of avian influenza virus: Recent advances in diagnostic technologies and surveillance strategies
title_sort prevention and control of avian influenza virus recent advances in diagnostic technologies and surveillance strategies
url https://doi.org/10.1038/s41467-025-58882-4
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