ATPase activity profiling of three human DExD/H-box RNA helicases

ATPase activity profiling of three human DExD/H-box RNA helicases

Human DExD/H-box RNA helicases are ubiquitous molecular motors that unwind and rearrange RNA secondary structures in an ATP-dependent manner. These enzymes play essential roles in nearly all aspects of RNA metabolism. While their biological functions are well-characterized, the kinetic mechanisms re...

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Bibliographic Details
Main Authors: Fengling Li, U Hang Chan, Julia Garcia Perez, Hong Zeng, Irene Chau, Yanjun Li, Almagul Seitova, Levon Halabelian
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:SLAS Discovery
Subjects:
RNA helicases
ATPase assay
Online Access:http://www.sciencedirect.com/science/article/pii/S247255522500022X
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