Caries Inhibition Potential of <italic>Salivarius</italic> M18 Probiotic in High-risk Children
Background: Preventive interventions that aim to halt or slow caries progression provides a practical solution for minimizing the problems stemming from caries. From the oral health perspective, the probiotic approach has been a popular method for modulating microbial communities. Aims: To evaluate...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Jaypee Brothers Medical Publisher
2022-08-01
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| Series: | Journal of South Asian Association of Pediatric Dentistry |
| Subjects: | |
| Online Access: | https://www.jsaapd.com/doi/JSAAPD/pdf/10.5005/jp-journals-10077-3227 |
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| Summary: | Background: Preventive interventions that aim to halt or slow caries progression provides a practical solution for minimizing the problems stemming from caries. From the oral health perspective, the probiotic approach has been a popular method for modulating microbial communities.
Aims: To evaluate the effect of <italic>Streptococcus salivarius</italic> M18 (<italic>Salivarius</italic> M18) probiotic in reducing plaque formation and lowering <italic>Streptococcus mutans</italic> counts when given as a daily supplement to children with high caries risk.
Settings and design: A total of 60 children in the age-group of 6–12 years and those classified as “high risk” for caries on the basis of caries management by risk assessment (CAMBRA) were included.
Materials and methods: Among the study participants, 30 were supplemented daily for 90 days with <italic>Salivarius</italic> M18 probiotic, and the remaining 30 served as untreated controls. All participants were subjected to evaluation of various parameters at baseline and 90 days following intervention. This included the decayed, missing, and filled teeth (DMFT)/dmft index, plaque index (Silness and Loe, 1964), and salivary <italic>S. mutans</italic> count (CFU/mL). The obtained data were compared with baseline scores; intergroup comparisons were made and subjected to statistical analysis.
Statistical analysis: Wilcoxon’s signed-rank test and Mann–Whitney <italic>U</italic> test were used for intra- and intergroup comparisons.
Results and conclusion: Intergroup comparison showed statistically highly significant difference with respect to <italic>S. mutans</italic> counts and plaque scores. The <italic>Salivarius</italic> M18 probiotic can be recommended as a means of caries preventive intervention for children at high risk. |
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| ISSN: | 2582-1024 |