Management of isolated recurrence of extramedullary myeloid tumor at a single site
Extramedullary myeloid tumors (EMMT) can precede, occur with or follow AML. Rarely, they can present as isolated relapses. We present a 9-year-old child with t (8, 21) positive AML who was treated with induction regimen and achieved remission. While on high-dose cytarabine consolidation, he had isol...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2013-01-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2013;volume=34;issue=2;spage=111;epage=113;aulast=Krishna |
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| _version_ | 1849724055471521792 |
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| author | Muddu Vamshi Krishna Ashok K Yadav Brijesh Arora Shripad D Banavali |
| author_facet | Muddu Vamshi Krishna Ashok K Yadav Brijesh Arora Shripad D Banavali |
| author_sort | Muddu Vamshi Krishna |
| collection | DOAJ |
| description | Extramedullary myeloid tumors (EMMT) can precede, occur with or follow AML. Rarely, they can present as isolated relapses. We present a 9-year-old child with t (8, 21) positive AML who was treated with induction regimen and achieved remission. While on high-dose cytarabine consolidation, he had isolated relapse in a single cervical lymph node with uninvolved marrow. He was treated with salvage chemotherapy alone. There are no clear guidelines for treatment of isolated extramedullary relapse. Chemotherapy, radiotherapy followed by stem cell transplant is the usual option. Our patient is unique for the unusual site of relapse and prolonged remission with cladribine-based chemotherapy, mitoxantrone-based consolidation, and oral maintenance therapy. |
| format | Article |
| id | doaj-art-ecffbabcdb624b9f8037094766fa92cb |
| institution | DOAJ |
| issn | 0971-5851 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-ecffbabcdb624b9f8037094766fa92cb2025-08-20T03:10:51ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512013-01-0134211111310.4103/0971-5851.116195Management of isolated recurrence of extramedullary myeloid tumor at a single siteMuddu Vamshi KrishnaAshok K YadavBrijesh AroraShripad D BanavaliExtramedullary myeloid tumors (EMMT) can precede, occur with or follow AML. Rarely, they can present as isolated relapses. We present a 9-year-old child with t (8, 21) positive AML who was treated with induction regimen and achieved remission. While on high-dose cytarabine consolidation, he had isolated relapse in a single cervical lymph node with uninvolved marrow. He was treated with salvage chemotherapy alone. There are no clear guidelines for treatment of isolated extramedullary relapse. Chemotherapy, radiotherapy followed by stem cell transplant is the usual option. Our patient is unique for the unusual site of relapse and prolonged remission with cladribine-based chemotherapy, mitoxantrone-based consolidation, and oral maintenance therapy.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2013;volume=34;issue=2;spage=111;epage=113;aulast=Krishna2-CDAAMLchemotherapyextramedullary relapse |
| spellingShingle | Muddu Vamshi Krishna Ashok K Yadav Brijesh Arora Shripad D Banavali Management of isolated recurrence of extramedullary myeloid tumor at a single site Indian Journal of Medical and Paediatric Oncology 2-CDA AML chemotherapy extramedullary relapse |
| title | Management of isolated recurrence of extramedullary myeloid tumor at a single site |
| title_full | Management of isolated recurrence of extramedullary myeloid tumor at a single site |
| title_fullStr | Management of isolated recurrence of extramedullary myeloid tumor at a single site |
| title_full_unstemmed | Management of isolated recurrence of extramedullary myeloid tumor at a single site |
| title_short | Management of isolated recurrence of extramedullary myeloid tumor at a single site |
| title_sort | management of isolated recurrence of extramedullary myeloid tumor at a single site |
| topic | 2-CDA AML chemotherapy extramedullary relapse |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2013;volume=34;issue=2;spage=111;epage=113;aulast=Krishna |
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