Application of Acoustic Cardiography in Assessment of Cardiac Function in Horses with Atrial Fibrillation Before and After Cardioversion

Left atrial mechanical dysfunction is common in horses following the treatment of atrial fibrillation (AF). This study aimed to evaluate the use of an acoustic cardiography monitor (Audicor<sup>®</sup>) in quantifying cardiac mechanical and hemodynamic function in horses with AF before a...

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Main Authors: Mélodie J. Schneider, Isabelle L. Piotrowski, Hannah K. Junge, Glenn van Steenkiste, Ingrid Vernemmen, Gunther van Loon, Colin C. Schwarzwald
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/15/13/1993
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author Mélodie J. Schneider
Isabelle L. Piotrowski
Hannah K. Junge
Glenn van Steenkiste
Ingrid Vernemmen
Gunther van Loon
Colin C. Schwarzwald
author_facet Mélodie J. Schneider
Isabelle L. Piotrowski
Hannah K. Junge
Glenn van Steenkiste
Ingrid Vernemmen
Gunther van Loon
Colin C. Schwarzwald
author_sort Mélodie J. Schneider
collection DOAJ
description Left atrial mechanical dysfunction is common in horses following the treatment of atrial fibrillation (AF). This study aimed to evaluate the use of an acoustic cardiography monitor (Audicor<sup>®</sup>) in quantifying cardiac mechanical and hemodynamic function in horses with AF before and after treatment and to correlate these findings with echocardiographic measures. Twenty-eight horses with AF and successful transvenous electrical cardioversion were included. Audicor<sup>®</sup> recordings with concomitant echocardiographic examinations were performed one day before, one day after, and two to seven days after cardioversion. Key variables measured by Audicor<sup>®</sup> included electromechanical activating time (EMAT), heart rate-corrected EMATc, left ventricular systolic time (LVST), heart rate-corrected LVSTc, systolic dysfunction index (SDI), and intensity and persistence of the third and fourth heart sound (S3, S4). A repeated-measures ANOVA with Tukey’s test was used to compare these variables over time, and linear regression and Bland–Altman analyses were applied to assess associations with echocardiographic findings. Following conversion to sinus rhythm, there was a significant decrease in EMATc and LVSTc (<i>p</i> < 0.0001) and a significant increase in LVST (<i>p</i> = 0.0001), indicating improved ventricular systolic function, with strong agreement between Audicor<sup>®</sup> snapshot and echocardiographic measures. However, S4 quantification did not show clinical value for assessing left atrial function after conversion.
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spelling doaj-art-ecfe3e5fbccb48d28dbf4d4d105de6042025-08-20T03:16:42ZengMDPI AGAnimals2076-26152025-07-011513199310.3390/ani15131993Application of Acoustic Cardiography in Assessment of Cardiac Function in Horses with Atrial Fibrillation Before and After CardioversionMélodie J. Schneider0Isabelle L. Piotrowski1Hannah K. Junge2Glenn van Steenkiste3Ingrid Vernemmen4Gunther van Loon5Colin C. Schwarzwald6Clinic for Equine Internal Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, SwitzerlandClinic for Equine Internal Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, SwitzerlandClinic for Equine Internal Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, SwitzerlandEquine Cardioteam Ghent, Department of Internal Medicine, Reproduction and Population Medicine, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, BelgiumEquine Cardioteam Ghent, Department of Internal Medicine, Reproduction and Population Medicine, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, BelgiumEquine Cardioteam Ghent, Department of Internal Medicine, Reproduction and Population Medicine, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, BelgiumClinic for Equine Internal Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, SwitzerlandLeft atrial mechanical dysfunction is common in horses following the treatment of atrial fibrillation (AF). This study aimed to evaluate the use of an acoustic cardiography monitor (Audicor<sup>®</sup>) in quantifying cardiac mechanical and hemodynamic function in horses with AF before and after treatment and to correlate these findings with echocardiographic measures. Twenty-eight horses with AF and successful transvenous electrical cardioversion were included. Audicor<sup>®</sup> recordings with concomitant echocardiographic examinations were performed one day before, one day after, and two to seven days after cardioversion. Key variables measured by Audicor<sup>®</sup> included electromechanical activating time (EMAT), heart rate-corrected EMATc, left ventricular systolic time (LVST), heart rate-corrected LVSTc, systolic dysfunction index (SDI), and intensity and persistence of the third and fourth heart sound (S3, S4). A repeated-measures ANOVA with Tukey’s test was used to compare these variables over time, and linear regression and Bland–Altman analyses were applied to assess associations with echocardiographic findings. Following conversion to sinus rhythm, there was a significant decrease in EMATc and LVSTc (<i>p</i> < 0.0001) and a significant increase in LVST (<i>p</i> = 0.0001), indicating improved ventricular systolic function, with strong agreement between Audicor<sup>®</sup> snapshot and echocardiographic measures. However, S4 quantification did not show clinical value for assessing left atrial function after conversion.https://www.mdpi.com/2076-2615/15/13/1993arrhythmiaphonocardiogramechocardiographycardiovascularAudicor<sup>®</sup>
spellingShingle Mélodie J. Schneider
Isabelle L. Piotrowski
Hannah K. Junge
Glenn van Steenkiste
Ingrid Vernemmen
Gunther van Loon
Colin C. Schwarzwald
Application of Acoustic Cardiography in Assessment of Cardiac Function in Horses with Atrial Fibrillation Before and After Cardioversion
Animals
arrhythmia
phonocardiogram
echocardiography
cardiovascular
Audicor<sup>®</sup>
title Application of Acoustic Cardiography in Assessment of Cardiac Function in Horses with Atrial Fibrillation Before and After Cardioversion
title_full Application of Acoustic Cardiography in Assessment of Cardiac Function in Horses with Atrial Fibrillation Before and After Cardioversion
title_fullStr Application of Acoustic Cardiography in Assessment of Cardiac Function in Horses with Atrial Fibrillation Before and After Cardioversion
title_full_unstemmed Application of Acoustic Cardiography in Assessment of Cardiac Function in Horses with Atrial Fibrillation Before and After Cardioversion
title_short Application of Acoustic Cardiography in Assessment of Cardiac Function in Horses with Atrial Fibrillation Before and After Cardioversion
title_sort application of acoustic cardiography in assessment of cardiac function in horses with atrial fibrillation before and after cardioversion
topic arrhythmia
phonocardiogram
echocardiography
cardiovascular
Audicor<sup>®</sup>
url https://www.mdpi.com/2076-2615/15/13/1993
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