Cognitive and Functional Impairment in Stroke Survivors with Basilar Artery Occlusive Disease

Background. Despite growing literature on posterior vascular disease, specific information about the cognitive and functional profiles of patients with basilar artery occlusion disease (BAOD) is scarce. The aims of this study were (1) to compare the cognitive statuses of BAOD survivors versus health...

Full description

Saved in:
Bibliographic Details
Main Authors: Kenia Repiso Campanholo, Adriana Bastos Conforto, Carolina Medeiros Rimkus, Eliane Correa Miotto
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2015/971514
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849690064990240768
author Kenia Repiso Campanholo
Adriana Bastos Conforto
Carolina Medeiros Rimkus
Eliane Correa Miotto
author_facet Kenia Repiso Campanholo
Adriana Bastos Conforto
Carolina Medeiros Rimkus
Eliane Correa Miotto
author_sort Kenia Repiso Campanholo
collection DOAJ
description Background. Despite growing literature on posterior vascular disease, specific information about the cognitive and functional profiles of patients with basilar artery occlusion disease (BAOD) is scarce. The aims of this study were (1) to compare the cognitive statuses of BAOD survivors versus healthy controls and (2) to correlate the functional capacity outcomes with the cognitive profiles of BAOD patients. Methods. Comprehensive cognitive and functional assessments were carried out in 28 patients with BAOD and 27 age- and education level-matched healthy controls. Results. Compared to matched controls, patients presented impairments in selective, sustained, and set-shifting attention, processing speed, visuospatial skills, mental flexibility, and monitoring rules. There were significant deficits in verbal episodic memory (immediate and delayed recall) and visuospatial episodic memory (immediate and delayed recall and recognition). Functional capacity outcomes were significantly related to the cognitive test results. Seventy-five percent of patients had a Modified Rankin Scale score of 0 or 1. Conclusions. Our results indicate good functional outcomes in a selected group of BAOD survivors, despite the presence of subnormal performance on some cognitive tests, including tests of attention, executive function, and long-term memory.
format Article
id doaj-art-ecfd11a96ce34974b0508d3d8a22d472
institution DOAJ
issn 0953-4180
1875-8584
language English
publishDate 2015-01-01
publisher Wiley
record_format Article
series Behavioural Neurology
spelling doaj-art-ecfd11a96ce34974b0508d3d8a22d4722025-08-20T03:21:26ZengWileyBehavioural Neurology0953-41801875-85842015-01-01201510.1155/2015/971514971514Cognitive and Functional Impairment in Stroke Survivors with Basilar Artery Occlusive DiseaseKenia Repiso Campanholo0Adriana Bastos Conforto1Carolina Medeiros Rimkus2Eliane Correa Miotto3Department of Neurology, University of São Paulo, 05403-000 São Paulo, SP, BrazilDepartment of Neurology, University of São Paulo, 05403-000 São Paulo, SP, BrazilDepartment of Radiology, University of São Paulo, 05403-000 São Paulo, SP, BrazilDepartment of Neurology, University of São Paulo, 05403-000 São Paulo, SP, BrazilBackground. Despite growing literature on posterior vascular disease, specific information about the cognitive and functional profiles of patients with basilar artery occlusion disease (BAOD) is scarce. The aims of this study were (1) to compare the cognitive statuses of BAOD survivors versus healthy controls and (2) to correlate the functional capacity outcomes with the cognitive profiles of BAOD patients. Methods. Comprehensive cognitive and functional assessments were carried out in 28 patients with BAOD and 27 age- and education level-matched healthy controls. Results. Compared to matched controls, patients presented impairments in selective, sustained, and set-shifting attention, processing speed, visuospatial skills, mental flexibility, and monitoring rules. There were significant deficits in verbal episodic memory (immediate and delayed recall) and visuospatial episodic memory (immediate and delayed recall and recognition). Functional capacity outcomes were significantly related to the cognitive test results. Seventy-five percent of patients had a Modified Rankin Scale score of 0 or 1. Conclusions. Our results indicate good functional outcomes in a selected group of BAOD survivors, despite the presence of subnormal performance on some cognitive tests, including tests of attention, executive function, and long-term memory.http://dx.doi.org/10.1155/2015/971514
spellingShingle Kenia Repiso Campanholo
Adriana Bastos Conforto
Carolina Medeiros Rimkus
Eliane Correa Miotto
Cognitive and Functional Impairment in Stroke Survivors with Basilar Artery Occlusive Disease
Behavioural Neurology
title Cognitive and Functional Impairment in Stroke Survivors with Basilar Artery Occlusive Disease
title_full Cognitive and Functional Impairment in Stroke Survivors with Basilar Artery Occlusive Disease
title_fullStr Cognitive and Functional Impairment in Stroke Survivors with Basilar Artery Occlusive Disease
title_full_unstemmed Cognitive and Functional Impairment in Stroke Survivors with Basilar Artery Occlusive Disease
title_short Cognitive and Functional Impairment in Stroke Survivors with Basilar Artery Occlusive Disease
title_sort cognitive and functional impairment in stroke survivors with basilar artery occlusive disease
url http://dx.doi.org/10.1155/2015/971514
work_keys_str_mv AT keniarepisocampanholo cognitiveandfunctionalimpairmentinstrokesurvivorswithbasilararteryocclusivedisease
AT adrianabastosconforto cognitiveandfunctionalimpairmentinstrokesurvivorswithbasilararteryocclusivedisease
AT carolinamedeirosrimkus cognitiveandfunctionalimpairmentinstrokesurvivorswithbasilararteryocclusivedisease
AT elianecorreamiotto cognitiveandfunctionalimpairmentinstrokesurvivorswithbasilararteryocclusivedisease