Excellent response to rituximab in a patient with recalcitrant epidermolysis bullosa acquisita: a case report
Epidermolysis Bullosa Acquisita is a rare, chronic autoimmune blistering disorder characterized by vesicles and bullae on the skin and mucous membranes. This condition, presenting typically in adulthood, is caused by autoantibodies against type VII collagen. Conventional treatments, including system...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-05-01
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| Series: | Journal of the Egyptian Women’s Dermatologic Society |
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| Online Access: | https://journals.lww.com/10.4103/jewd.jewd_109_24 |
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| _version_ | 1850131201337065472 |
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| author | Fahad Alrashidi Khalid Nabil Nagshabandi Ruaa Alharithy |
| author_facet | Fahad Alrashidi Khalid Nabil Nagshabandi Ruaa Alharithy |
| author_sort | Fahad Alrashidi |
| collection | DOAJ |
| description | Epidermolysis Bullosa Acquisita is a rare, chronic autoimmune blistering disorder characterized by vesicles and bullae on the skin and mucous membranes. This condition, presenting typically in adulthood, is caused by autoantibodies against type VII collagen. Conventional treatments, including systemic corticosteroids and immunosuppressants, often fail to achieve long-term remission. Biologic agents like rituximab have shown promise in managing refractory cases. This report presents a case of a 27-year-old female with recalcitrant epidermolysis bullosa acquisita successfully managed after starting rituximab therapy. |
| format | Article |
| id | doaj-art-ecfaeebc69bd455a97f250451bedd7a7 |
| institution | OA Journals |
| issn | 2090-2565 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of the Egyptian Women’s Dermatologic Society |
| spelling | doaj-art-ecfaeebc69bd455a97f250451bedd7a72025-08-20T02:32:29ZengWolters Kluwer Medknow PublicationsJournal of the Egyptian Women’s Dermatologic Society2090-25652025-05-0122217017410.4103/jewd.jewd_109_24Excellent response to rituximab in a patient with recalcitrant epidermolysis bullosa acquisita: a case reportFahad AlrashidiKhalid Nabil NagshabandiRuaa AlharithyEpidermolysis Bullosa Acquisita is a rare, chronic autoimmune blistering disorder characterized by vesicles and bullae on the skin and mucous membranes. This condition, presenting typically in adulthood, is caused by autoantibodies against type VII collagen. Conventional treatments, including systemic corticosteroids and immunosuppressants, often fail to achieve long-term remission. Biologic agents like rituximab have shown promise in managing refractory cases. This report presents a case of a 27-year-old female with recalcitrant epidermolysis bullosa acquisita successfully managed after starting rituximab therapy.https://journals.lww.com/10.4103/jewd.jewd_109_24biologicsepidermolysis bullosa acquisitarituximab |
| spellingShingle | Fahad Alrashidi Khalid Nabil Nagshabandi Ruaa Alharithy Excellent response to rituximab in a patient with recalcitrant epidermolysis bullosa acquisita: a case report Journal of the Egyptian Women’s Dermatologic Society biologics epidermolysis bullosa acquisita rituximab |
| title | Excellent response to rituximab in a patient with recalcitrant epidermolysis bullosa acquisita: a case report |
| title_full | Excellent response to rituximab in a patient with recalcitrant epidermolysis bullosa acquisita: a case report |
| title_fullStr | Excellent response to rituximab in a patient with recalcitrant epidermolysis bullosa acquisita: a case report |
| title_full_unstemmed | Excellent response to rituximab in a patient with recalcitrant epidermolysis bullosa acquisita: a case report |
| title_short | Excellent response to rituximab in a patient with recalcitrant epidermolysis bullosa acquisita: a case report |
| title_sort | excellent response to rituximab in a patient with recalcitrant epidermolysis bullosa acquisita a case report |
| topic | biologics epidermolysis bullosa acquisita rituximab |
| url | https://journals.lww.com/10.4103/jewd.jewd_109_24 |
| work_keys_str_mv | AT fahadalrashidi excellentresponsetorituximabinapatientwithrecalcitrantepidermolysisbullosaacquisitaacasereport AT khalidnabilnagshabandi excellentresponsetorituximabinapatientwithrecalcitrantepidermolysisbullosaacquisitaacasereport AT ruaaalharithy excellentresponsetorituximabinapatientwithrecalcitrantepidermolysisbullosaacquisitaacasereport |