Unraveling the interplay between mesenchymal stem cells, gut microbiota, and systemic sclerosis: therapeutic implications

Unraveling the interplay between mesenchymal stem cells, gut microbiota, and systemic sclerosis: therapeutic implications

ABSTRACT Systemic sclerosis (SSc) is an autoimmune disease with progressive fibrotic disorders in multiple organs. Mesenchymal stem cells (MSCs) have shown great potential in treating SSc, but the exact regulatory mechanism is not fully understood. In this study, we used human umbilical cord-derived...

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Bibliographic Details
Main Authors: Lili Zhang, Hui Wang, Lu Zhao, Jin Zhang, Wenchang Sun, Jinjin Chu, Haobin Zhao, Chunjuan Yang, Shushan Yan, Xiaohua Chen, Donghua Xu
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:Microbiology Spectrum
Subjects:
mesenchymal stem cells
systemic sclerosis
metabolism
2bRAD sequence
gut microbiota
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01576-24
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