A comparison between quantitative gated myocardial perfusion scintigraphy and strain echocardiography as indicators of ventricular functions in patients with anterior myocardial infarction

The purpose of this study is to compare the strain echocardiographic and scintigraphic parameters for evaluating of the left ventricular (LV) functions in patients with anterior myocardial infarction (MI). Fifty-four patients (male/female: 36/18; mean age 62 ± 13 years) with anterior MI were prospec...

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Main Authors: Seyhan Karacavus, Ahmet Celik, Ahmet Tutus, Mustafa Kula, Abdurrahman Oguzhan, Ibrahim Ozdogru, Nihat Kalay
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2014-07-01
Series:World Journal of Nuclear Medicine
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.144819
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author Seyhan Karacavus
Ahmet Celik
Ahmet Tutus
Mustafa Kula
Abdurrahman Oguzhan
Ibrahim Ozdogru
Nihat Kalay
author_facet Seyhan Karacavus
Ahmet Celik
Ahmet Tutus
Mustafa Kula
Abdurrahman Oguzhan
Ibrahim Ozdogru
Nihat Kalay
author_sort Seyhan Karacavus
collection DOAJ
description The purpose of this study is to compare the strain echocardiographic and scintigraphic parameters for evaluating of the left ventricular (LV) functions in patients with anterior myocardial infarction (MI). Fifty-four patients (male/female: 36/18; mean age 62 ± 13 years) with anterior MI were prospectively enrolled. All patients were performed gated myocardial perfusion scintigraphy gated single-photon emission computed tomography (GSPECT) and echocardiography (EC). GSPECT data were processed and analyzed using 4D-MSPECT (4DM, Invia Medical Imaging Solutions, Ann Arbor, MI, USA). The echocardiographic strain (S) and strain rate (SR) values were calculated. The results obtained by these techniques were compared each other. A total of 918 segments of LV wall were evaluated. In all patients, 385 segments were automatically scored as normokinetic, 206 as hypokinetic, 122 as akinetic, 205 as dyskinetic and 300 as normal thickening, 348 as decrease thickening and 270 as no thickening. The means of S and SR values in thickening and motion score groups according to GSPECT were statistically different from each other (P < 0.001). There was a negative significant correlation between LV wall thickening sum score and S and SR and between LV wall motion sum score and S and SR (P < 0.001). There was a good correlation between GSPECT and echocardiographic LV-ejection fraction (r = 0.7, P < 0.001). GSPECT and strain EC are similar in quantitative grading of the severity of regional and global myocardial dysfunction in patients with anterior MI and these techniques provide valuable diagnostic information.
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spelling doaj-art-ecf778c87c4f4bf5afc85845e1d981f92025-08-20T03:48:36ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122014-07-01130318418910.4103/1450-1147.144819A comparison between quantitative gated myocardial perfusion scintigraphy and strain echocardiography as indicators of ventricular functions in patients with anterior myocardial infarctionSeyhan Karacavus0Ahmet Celik1Ahmet Tutus2Mustafa Kula3Abdurrahman Oguzhan4Ibrahim Ozdogru5Nihat Kalay6Department of Nuclear Medicine, School of Medicine, Bozok University, YozgatDepartment of Cardiology, School of Medicine, Mersin University, MersinDepartment of Nuclear Medicine, School of Medicine, Erciyes University, Kayseri, TurkeyDepartment of Nuclear Medicine, School of Medicine, Erciyes University, Kayseri, TurkeyDepartment of Cardiology, School of Medicine, Erciyes University, Kayseri, TurkeyDepartment of Cardiology, School of Medicine, Erciyes University, Kayseri, TurkeyDepartment of Cardiology, School of Medicine, Erciyes University, Kayseri, TurkeyThe purpose of this study is to compare the strain echocardiographic and scintigraphic parameters for evaluating of the left ventricular (LV) functions in patients with anterior myocardial infarction (MI). Fifty-four patients (male/female: 36/18; mean age 62 ± 13 years) with anterior MI were prospectively enrolled. All patients were performed gated myocardial perfusion scintigraphy gated single-photon emission computed tomography (GSPECT) and echocardiography (EC). GSPECT data were processed and analyzed using 4D-MSPECT (4DM, Invia Medical Imaging Solutions, Ann Arbor, MI, USA). The echocardiographic strain (S) and strain rate (SR) values were calculated. The results obtained by these techniques were compared each other. A total of 918 segments of LV wall were evaluated. In all patients, 385 segments were automatically scored as normokinetic, 206 as hypokinetic, 122 as akinetic, 205 as dyskinetic and 300 as normal thickening, 348 as decrease thickening and 270 as no thickening. The means of S and SR values in thickening and motion score groups according to GSPECT were statistically different from each other (P < 0.001). There was a negative significant correlation between LV wall thickening sum score and S and SR and between LV wall motion sum score and S and SR (P < 0.001). There was a good correlation between GSPECT and echocardiographic LV-ejection fraction (r = 0.7, P < 0.001). GSPECT and strain EC are similar in quantitative grading of the severity of regional and global myocardial dysfunction in patients with anterior MI and these techniques provide valuable diagnostic information.http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.144819left ventricular functionmyocardial infarctionmyocardial scintigraphystrain echocardiography
spellingShingle Seyhan Karacavus
Ahmet Celik
Ahmet Tutus
Mustafa Kula
Abdurrahman Oguzhan
Ibrahim Ozdogru
Nihat Kalay
A comparison between quantitative gated myocardial perfusion scintigraphy and strain echocardiography as indicators of ventricular functions in patients with anterior myocardial infarction
World Journal of Nuclear Medicine
left ventricular function
myocardial infarction
myocardial scintigraphy
strain echocardiography
title A comparison between quantitative gated myocardial perfusion scintigraphy and strain echocardiography as indicators of ventricular functions in patients with anterior myocardial infarction
title_full A comparison between quantitative gated myocardial perfusion scintigraphy and strain echocardiography as indicators of ventricular functions in patients with anterior myocardial infarction
title_fullStr A comparison between quantitative gated myocardial perfusion scintigraphy and strain echocardiography as indicators of ventricular functions in patients with anterior myocardial infarction
title_full_unstemmed A comparison between quantitative gated myocardial perfusion scintigraphy and strain echocardiography as indicators of ventricular functions in patients with anterior myocardial infarction
title_short A comparison between quantitative gated myocardial perfusion scintigraphy and strain echocardiography as indicators of ventricular functions in patients with anterior myocardial infarction
title_sort comparison between quantitative gated myocardial perfusion scintigraphy and strain echocardiography as indicators of ventricular functions in patients with anterior myocardial infarction
topic left ventricular function
myocardial infarction
myocardial scintigraphy
strain echocardiography
url http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.144819
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