Hypoxia-related signatures predicts survival, immunosuppression and PARP inhibitor resistance in HCC
Abstract Background Despite extensive research on hypoxia in hepatocellular carcinoma (HCC), previous studies have relied on pre-existing hypoxia gene sets, limiting their specificity. We developed a novel approach using direct comparison of hypoxic versus normoxic HCC cell lines to establish a more...
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| Main Authors: | Min Su, Haibo Duan, Yu Gu, Jianfu Zhao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-06-01
|
| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02923-3 |
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