Advancements in diagnostics for visceral leishmaniasis: Current landscape and future directions
Visceral leishmaniasis (VL) is a significant global health concern, causing considerable morbidity and mortality. The prevalence of VL is influenced by environmental conditions and limited access to healthcare services. Accurate diagnostics are crucial for monitoring and controlling disease spread....
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| Format: | Article |
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Wolters Kluwer Medknow Publications
2025-06-01
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| Series: | Annals of Medical Science and Research |
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| Online Access: | https://journals.lww.com/10.4103/amsr.amsr_47_24 |
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| author | Mudsser Azam Bharti Singhal Ruchi Singh |
| author_facet | Mudsser Azam Bharti Singhal Ruchi Singh |
| author_sort | Mudsser Azam |
| collection | DOAJ |
| description | Visceral leishmaniasis (VL) is a significant global health concern, causing considerable morbidity and mortality. The prevalence of VL is influenced by environmental conditions and limited access to healthcare services. Accurate diagnostics are crucial for monitoring and controlling disease spread. This review examines current advancements in diagnostic technologies for VL, focusing on the need for highly sensitive, easily applicable, and affordable diagnostics. Parasitological examination, serological tests, molecular assays, and rapid diagnostic tests are discussed in detail, highlighting their strengths and limitations. Furthermore, we have discussed global efforts and initiatives aimed at improving diagnostics and conclude by exploring future directions in the field. Improved diagnostic capability, effective treatment regimes, and comprehensive public health initiatives are essential to reduce the global burden of VL. Furthermore, research and development are needed to enhance diagnostic tools for VL, particularly in resource-poor endemic countries. |
| format | Article |
| id | doaj-art-ecef119a7fda4072afd8400a2d2fd410 |
| institution | Kabale University |
| issn | 2949-785X 2949-7868 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Medical Science and Research |
| spelling | doaj-art-ecef119a7fda4072afd8400a2d2fd4102025-08-20T03:36:14ZengWolters Kluwer Medknow PublicationsAnnals of Medical Science and Research2949-785X2949-78682025-06-014Suppl 1S78S8610.4103/amsr.amsr_47_24Advancements in diagnostics for visceral leishmaniasis: Current landscape and future directionsMudsser AzamBharti SinghalRuchi SinghVisceral leishmaniasis (VL) is a significant global health concern, causing considerable morbidity and mortality. The prevalence of VL is influenced by environmental conditions and limited access to healthcare services. Accurate diagnostics are crucial for monitoring and controlling disease spread. This review examines current advancements in diagnostic technologies for VL, focusing on the need for highly sensitive, easily applicable, and affordable diagnostics. Parasitological examination, serological tests, molecular assays, and rapid diagnostic tests are discussed in detail, highlighting their strengths and limitations. Furthermore, we have discussed global efforts and initiatives aimed at improving diagnostics and conclude by exploring future directions in the field. Improved diagnostic capability, effective treatment regimes, and comprehensive public health initiatives are essential to reduce the global burden of VL. Furthermore, research and development are needed to enhance diagnostic tools for VL, particularly in resource-poor endemic countries.https://journals.lww.com/10.4103/amsr.amsr_47_24diagnosisrapid testvisceral leishmaniasis |
| spellingShingle | Mudsser Azam Bharti Singhal Ruchi Singh Advancements in diagnostics for visceral leishmaniasis: Current landscape and future directions Annals of Medical Science and Research diagnosis rapid test visceral leishmaniasis |
| title | Advancements in diagnostics for visceral leishmaniasis: Current landscape and future directions |
| title_full | Advancements in diagnostics for visceral leishmaniasis: Current landscape and future directions |
| title_fullStr | Advancements in diagnostics for visceral leishmaniasis: Current landscape and future directions |
| title_full_unstemmed | Advancements in diagnostics for visceral leishmaniasis: Current landscape and future directions |
| title_short | Advancements in diagnostics for visceral leishmaniasis: Current landscape and future directions |
| title_sort | advancements in diagnostics for visceral leishmaniasis current landscape and future directions |
| topic | diagnosis rapid test visceral leishmaniasis |
| url | https://journals.lww.com/10.4103/amsr.amsr_47_24 |
| work_keys_str_mv | AT mudsserazam advancementsindiagnosticsforvisceralleishmaniasiscurrentlandscapeandfuturedirections AT bhartisinghal advancementsindiagnosticsforvisceralleishmaniasiscurrentlandscapeandfuturedirections AT ruchisingh advancementsindiagnosticsforvisceralleishmaniasiscurrentlandscapeandfuturedirections |