Cyclopentadienyl Ruthenium(II) Complex-Mediated Oxidation of Benzylic and Allylic Alcohols to Corresponding Aldehydes
This work reports an efficient method for the oxidation reaction of aliphatic, aromatic allylic, and benzylic alcohols into aldehydes catalyzed by the cyclopentadienyl ruthenium(II) complex (RuCpCl(PPh3)2) with bubbled O2. Through further optimizing controlled studies, the tendency order of oxidatio...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Heteroatom Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2019/5053702 |
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| author | Ching-Yuh Chern Ching-Chun Tseng Rong-Hong Hsiao Fung Fuh Wong Yueh-Hsiung Kuo |
| author_facet | Ching-Yuh Chern Ching-Chun Tseng Rong-Hong Hsiao Fung Fuh Wong Yueh-Hsiung Kuo |
| author_sort | Ching-Yuh Chern |
| collection | DOAJ |
| description | This work reports an efficient method for the oxidation reaction of aliphatic, aromatic allylic, and benzylic alcohols into aldehydes catalyzed by the cyclopentadienyl ruthenium(II) complex (RuCpCl(PPh3)2) with bubbled O2. Through further optimizing controlled studies, the tendency order of oxidation reactivity was determined as follows: benzylic alcohols > aromatic allylic alcohols >> aliphatic alcohols. In addition, this method has several advantages, including a small amount of catalyst (0.5 mol%) and selective application of high discrimination activity of aliphatic, aromatic allylic, and benzylic alcohols. |
| format | Article |
| id | doaj-art-ece78e5f4e484871a8f354d2c35a2a36 |
| institution | DOAJ |
| issn | 1042-7163 1098-1071 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Heteroatom Chemistry |
| spelling | doaj-art-ece78e5f4e484871a8f354d2c35a2a362025-08-20T03:21:26ZengWileyHeteroatom Chemistry1042-71631098-10712019-01-01201910.1155/2019/50537025053702Cyclopentadienyl Ruthenium(II) Complex-Mediated Oxidation of Benzylic and Allylic Alcohols to Corresponding AldehydesChing-Yuh Chern0Ching-Chun Tseng1Rong-Hong Hsiao2Fung Fuh Wong3Yueh-Hsiung Kuo4Department of Applied Chemistry, National Chia-Yi University, Chia-Yi 60004, TaiwanThe Ph.D. Program for Biotech Pharmaceutical Industry, China Medical University, No. 91, Hsueh-Shih Rd., Taichung 40402, TaiwanSchool of Pharmacy, China Medical University, No. 91, Hsueh-Shih Rd., Taichung 40402, TaiwanThe Ph.D. Program for Biotech Pharmaceutical Industry, China Medical University, No. 91, Hsueh-Shih Rd., Taichung 40402, TaiwanDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 40402, TaiwanThis work reports an efficient method for the oxidation reaction of aliphatic, aromatic allylic, and benzylic alcohols into aldehydes catalyzed by the cyclopentadienyl ruthenium(II) complex (RuCpCl(PPh3)2) with bubbled O2. Through further optimizing controlled studies, the tendency order of oxidation reactivity was determined as follows: benzylic alcohols > aromatic allylic alcohols >> aliphatic alcohols. In addition, this method has several advantages, including a small amount of catalyst (0.5 mol%) and selective application of high discrimination activity of aliphatic, aromatic allylic, and benzylic alcohols.http://dx.doi.org/10.1155/2019/5053702 |
| spellingShingle | Ching-Yuh Chern Ching-Chun Tseng Rong-Hong Hsiao Fung Fuh Wong Yueh-Hsiung Kuo Cyclopentadienyl Ruthenium(II) Complex-Mediated Oxidation of Benzylic and Allylic Alcohols to Corresponding Aldehydes Heteroatom Chemistry |
| title | Cyclopentadienyl Ruthenium(II) Complex-Mediated Oxidation of Benzylic and Allylic Alcohols to Corresponding Aldehydes |
| title_full | Cyclopentadienyl Ruthenium(II) Complex-Mediated Oxidation of Benzylic and Allylic Alcohols to Corresponding Aldehydes |
| title_fullStr | Cyclopentadienyl Ruthenium(II) Complex-Mediated Oxidation of Benzylic and Allylic Alcohols to Corresponding Aldehydes |
| title_full_unstemmed | Cyclopentadienyl Ruthenium(II) Complex-Mediated Oxidation of Benzylic and Allylic Alcohols to Corresponding Aldehydes |
| title_short | Cyclopentadienyl Ruthenium(II) Complex-Mediated Oxidation of Benzylic and Allylic Alcohols to Corresponding Aldehydes |
| title_sort | cyclopentadienyl ruthenium ii complex mediated oxidation of benzylic and allylic alcohols to corresponding aldehydes |
| url | http://dx.doi.org/10.1155/2019/5053702 |
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