Exploring research frontiers and emerging trends of tyrosine kinase inhibitors in the treatment of colorectal cancer

Exploring research frontiers and emerging trends of tyrosine kinase inhibitors in the treatment of colorectal cancer

Abstract Background Tyrosine kinase inhibitors (TKIs) are a class of molecular targeted drugs designed to selectively inhibit tyrosine kinase activity associated with oncogenic signaling pathways and drivers, and have emerged as key therapeutic agents for colorectal cancer (CRC). The purpose of this...

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Bibliographic Details
Main Authors: Xiaosong Li, Zhenlong Chen, Jie Yin, Xiping Shen, Hang Li
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
Colorectal cancer
Tyrosine kinase inhibitors
Targeted therapy
Immunotherapy
Tumor microenvironment
Online Access:https://doi.org/10.1186/s12885-025-14639-2
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