Abdominal Fat and Sarcopenia in Women Significantly Alter Osteoblasts Homeostasis In Vitro by a WNT/β-Catenin Dependent Mechanism

Abdominal Fat and Sarcopenia in Women Significantly Alter Osteoblasts Homeostasis In Vitro by a WNT/β-Catenin Dependent Mechanism

Obesity and sarcopenia have been associated with mineral metabolism derangement and low bone mineral density (BMD). We investigated whether imbalance of serum factors in obese or obese sarcopenic patients could affect bone cell activity in vitro. To evaluate and characterize potential cellular and m...

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Main Authors: Francesca Wannenes, Vincenza Papa, Emanuela A. Greco, Rachele Fornari, Chiara Marocco, Carlo Baldari, Luigi Di Luigi, Gian Pietro Emerenziani, Eleonora Poggiogalle, Laura Guidetti, Lorenzo M. Donini, Andrea Lenzi, Silvia Migliaccio
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2014/278316
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