A Two-Level Rule-Mining Approach to Classify Breast Cancer Patterns Using Adaptive Directed Mutation and Genetic Algorithm

Breast cancer represents a significant public health concern in both Western countries and Asia. Accurate and early detection is critical to improving long-term patient survival. For physicians to understand the classification and decision rules and to evaluate their results, it is preferable to use...

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Main Authors: Hui-Ching Wu, Ming-Hseng Tseng
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Eng
Subjects:
Online Access:https://www.mdpi.com/2673-4117/6/7/154
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author Hui-Ching Wu
Ming-Hseng Tseng
author_facet Hui-Ching Wu
Ming-Hseng Tseng
author_sort Hui-Ching Wu
collection DOAJ
description Breast cancer represents a significant public health concern in both Western countries and Asia. Accurate and early detection is critical to improving long-term patient survival. For physicians to understand the classification and decision rules and to evaluate their results, it is preferable to use white box approaches to develop prediction models. This paper proposes a novel classification technique for extracting malignant prediction rules from training datasets containing numerical and binary nominal attributes. The classification technique introduced in this study facilitates the discovery of breast cancer patterns by integrating a real-coded genetic algorithm, an adaptive directed mutation operator, and a two-level malignant-rule-mining process. The experimental results, compared with existing rule-based methods from previous studies, demonstrate that the proposed approach generates simple and interpretable decision rules and effectively identifies patterns that lead to accurate breast cancer classification.
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spelling doaj-art-ecda25a823de4c26b34ed0b865844d822025-08-20T02:45:34ZengMDPI AGEng2673-41172025-07-016715410.3390/eng6070154A Two-Level Rule-Mining Approach to Classify Breast Cancer Patterns Using Adaptive Directed Mutation and Genetic AlgorithmHui-Ching Wu0Ming-Hseng Tseng1Department of Medical Sociology and Social Work, Chung Shan Medical University, Taichung 402, TaiwanDepartment of Medical Informatics, Chung Shan Medical University, Taichung 402, TaiwanBreast cancer represents a significant public health concern in both Western countries and Asia. Accurate and early detection is critical to improving long-term patient survival. For physicians to understand the classification and decision rules and to evaluate their results, it is preferable to use white box approaches to develop prediction models. This paper proposes a novel classification technique for extracting malignant prediction rules from training datasets containing numerical and binary nominal attributes. The classification technique introduced in this study facilitates the discovery of breast cancer patterns by integrating a real-coded genetic algorithm, an adaptive directed mutation operator, and a two-level malignant-rule-mining process. The experimental results, compared with existing rule-based methods from previous studies, demonstrate that the proposed approach generates simple and interpretable decision rules and effectively identifies patterns that lead to accurate breast cancer classification.https://www.mdpi.com/2673-4117/6/7/154real-coded genetic algorithmadaptive directed mutationtwo-level malignant rulesbreast cancer
spellingShingle Hui-Ching Wu
Ming-Hseng Tseng
A Two-Level Rule-Mining Approach to Classify Breast Cancer Patterns Using Adaptive Directed Mutation and Genetic Algorithm
Eng
real-coded genetic algorithm
adaptive directed mutation
two-level malignant rules
breast cancer
title A Two-Level Rule-Mining Approach to Classify Breast Cancer Patterns Using Adaptive Directed Mutation and Genetic Algorithm
title_full A Two-Level Rule-Mining Approach to Classify Breast Cancer Patterns Using Adaptive Directed Mutation and Genetic Algorithm
title_fullStr A Two-Level Rule-Mining Approach to Classify Breast Cancer Patterns Using Adaptive Directed Mutation and Genetic Algorithm
title_full_unstemmed A Two-Level Rule-Mining Approach to Classify Breast Cancer Patterns Using Adaptive Directed Mutation and Genetic Algorithm
title_short A Two-Level Rule-Mining Approach to Classify Breast Cancer Patterns Using Adaptive Directed Mutation and Genetic Algorithm
title_sort two level rule mining approach to classify breast cancer patterns using adaptive directed mutation and genetic algorithm
topic real-coded genetic algorithm
adaptive directed mutation
two-level malignant rules
breast cancer
url https://www.mdpi.com/2673-4117/6/7/154
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