The Procoagulant and Fibrinolytic Balance of Extracellular Vesicles Predicts Mortality in Septic Shock Patients

The Procoagulant and Fibrinolytic Balance of Extracellular Vesicles Predicts Mortality in Septic Shock Patients

ABSTRACT Septic shock is characterised by abnormal coagulation activation with defective fibrinolysis, leading to a high mortality rate. Cellular activation triggers the release of extracellular vesicles (EVs) conveying both procoagulant and fibrinolytic activities. We investigated whether the balan...

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Main Authors: Romaric Lacroix, Coralie Judicone, Karim Harti Souab, Amandine Bonifay, Anderson Loundou, Tarik Bouriche, Sylvie Cointe, Loris Vallier, Evelyne Abdili, Laurent Arnaud, Stéphane Robert, Philippe Poncelet, Charlotte Grosdidier, Pierre Morange, Eva Cochery‐Nouvellon, Sylvie Bouvier, Jean‐Christophe Gris, Jean‐Yves Lefrant, Marc Leone, Jacques Albanese, Françoise Dignat‐George
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Journal of Extracellular Vesicles
Online Access:https://doi.org/10.1002/jev2.70073
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