25(OH)D Status in Metabolic Syndrome, Metabolic Syndrome Components, and Healthy Adult

Background: Vitamin D supplementation to prevent Metabolic Syndrome (MetS) has been widely implemented in developed countries and is now being introduced in developing countries. However, recent studies have shown no association between vitamin D and MetS in adults. Objectives: This study aims to...

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Main Authors: Efriwati Efriwati, Fitrah Ernawati, Nunung Nurjanah, Elisa Diana Julianti, Galih Kusuma Aji, Dian Sundari, Fifi Retiaty, Aya Yuriestia Arifin
Format: Article
Language:English
Published: Universitas Airlangga 2024-11-01
Series:Amerta Nutrition
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Online Access:https://e-journal.unair.ac.id/AMNT/article/view/62440
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author Efriwati Efriwati
Fitrah Ernawati
Nunung Nurjanah
Elisa Diana Julianti
Galih Kusuma Aji
Dian Sundari
Fifi Retiaty
Aya Yuriestia Arifin
author_facet Efriwati Efriwati
Fitrah Ernawati
Nunung Nurjanah
Elisa Diana Julianti
Galih Kusuma Aji
Dian Sundari
Fifi Retiaty
Aya Yuriestia Arifin
author_sort Efriwati Efriwati
collection DOAJ
description Background: Vitamin D supplementation to prevent Metabolic Syndrome (MetS) has been widely implemented in developed countries and is now being introduced in developing countries. However, recent studies have shown no association between vitamin D and MetS in adults. Objectives: This study aims to obtain a profile of vitamin D values ​​in adults and explore vitamin D status in MetS patients, MetS components, and healthy adults. Methods: This research design was a cross-sectional study, utilizing both secondary and primary data from the research on the Risk Factors for Non-Communicable Diseases (RF-NCD) longitudinal study in 2021. Serum 25(OH)D levels in 956 adult respondents were determined by Enzyme-linked Immune Assay (ELISA) analysis using Stored Biological Material (SBM) serum from the 2021 RF-NCD longitudinal study. The ANOVA test was used to determine differences in vitamin D levels in various physiological conditions of respondents (MetS, MetS components, and healthy people). Results: A total of 68.5% of respondents had inadequate (deficiency and insufficiency) serum vitamin D levels, with an average of 26.5 ng/mL. The average vitamin D levels between MetS patients, MetS components, and healthy people were not significantly different (p-value>0.05). However, the number or percentage of respondents with 25(OH)D deficiency in the MetS group (12.1%) was higher than other physiological conditions. Conclusions: Most of the respondents in this study have inadequate vitamin D levels. The average vitamin D levels did not differ between physiological conditions. Further studies are needed on other micronutrient factors that affect the incidence of MetS and its components.
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publishDate 2024-11-01
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spelling doaj-art-ecd47593d1ee49c3a4fac3546b3cfd382025-08-20T02:28:00ZengUniversitas AirlanggaAmerta Nutrition2580-11632580-97762024-11-018461962410.20473/amnt.v8i4.2024.619-6246060725(OH)D Status in Metabolic Syndrome, Metabolic Syndrome Components, and Healthy AdultEfriwati Efriwati0https://orcid.org/0000-0001-5969-085XFitrah Ernawati1https://orcid.org/0009-0003-2986-4646Nunung Nurjanah2https://orcid.org/0000-0003-0296-1721Elisa Diana Julianti3https://orcid.org/0009-0004-1853-4331Galih Kusuma Aji4https://orcid.org/0000-0002-1575-197XDian Sundari5https://orcid.org/0009-0005-5061-630XFifi Retiaty6https://orcid.org/0000-0002-0033-4532Aya Yuriestia Arifin7https://orcid.org/0000-0001-7005-2285Center for Public Health and Nutrition Research, National Research and Innovation Agency, Cibinong Science Center, BogorCenter for Public Health and Nutrition Research, National Research and Innovation Agency, Cibinong Science Center, BogorCenter for Public Health and Nutrition Research, National Research and Innovation Agency, Cibinong Science Center, BogorCenter for Public Health and Nutrition Research, National Research and Innovation Agency, Cibinong Science Center, BogorResearch Center for Agroindustry, National Research and Innovation Agency, BJ Habibie Science Center, Setu, Tangerang Selatan, BantenCenter for Public Health and Nutrition Research, National Research and Innovation Agency, Cibinong Science Center, BogorCenter for Public Health and Nutrition Research, National Research and Innovation Agency, Cibinong Science Center, BogorCenter for Public Health and Nutrition Research, National Research and Innovation Agency, Cibinong Science Center, BogorBackground: Vitamin D supplementation to prevent Metabolic Syndrome (MetS) has been widely implemented in developed countries and is now being introduced in developing countries. However, recent studies have shown no association between vitamin D and MetS in adults. Objectives: This study aims to obtain a profile of vitamin D values ​​in adults and explore vitamin D status in MetS patients, MetS components, and healthy adults. Methods: This research design was a cross-sectional study, utilizing both secondary and primary data from the research on the Risk Factors for Non-Communicable Diseases (RF-NCD) longitudinal study in 2021. Serum 25(OH)D levels in 956 adult respondents were determined by Enzyme-linked Immune Assay (ELISA) analysis using Stored Biological Material (SBM) serum from the 2021 RF-NCD longitudinal study. The ANOVA test was used to determine differences in vitamin D levels in various physiological conditions of respondents (MetS, MetS components, and healthy people). Results: A total of 68.5% of respondents had inadequate (deficiency and insufficiency) serum vitamin D levels, with an average of 26.5 ng/mL. The average vitamin D levels between MetS patients, MetS components, and healthy people were not significantly different (p-value>0.05). However, the number or percentage of respondents with 25(OH)D deficiency in the MetS group (12.1%) was higher than other physiological conditions. Conclusions: Most of the respondents in this study have inadequate vitamin D levels. The average vitamin D levels did not differ between physiological conditions. Further studies are needed on other micronutrient factors that affect the incidence of MetS and its components.https://e-journal.unair.ac.id/AMNT/article/view/62440adultsmetabolic syndromemicronutrientsvitamin d deficiency
spellingShingle Efriwati Efriwati
Fitrah Ernawati
Nunung Nurjanah
Elisa Diana Julianti
Galih Kusuma Aji
Dian Sundari
Fifi Retiaty
Aya Yuriestia Arifin
25(OH)D Status in Metabolic Syndrome, Metabolic Syndrome Components, and Healthy Adult
Amerta Nutrition
adults
metabolic syndrome
micronutrients
vitamin d deficiency
title 25(OH)D Status in Metabolic Syndrome, Metabolic Syndrome Components, and Healthy Adult
title_full 25(OH)D Status in Metabolic Syndrome, Metabolic Syndrome Components, and Healthy Adult
title_fullStr 25(OH)D Status in Metabolic Syndrome, Metabolic Syndrome Components, and Healthy Adult
title_full_unstemmed 25(OH)D Status in Metabolic Syndrome, Metabolic Syndrome Components, and Healthy Adult
title_short 25(OH)D Status in Metabolic Syndrome, Metabolic Syndrome Components, and Healthy Adult
title_sort 25 oh d status in metabolic syndrome metabolic syndrome components and healthy adult
topic adults
metabolic syndrome
micronutrients
vitamin d deficiency
url https://e-journal.unair.ac.id/AMNT/article/view/62440
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