Major Ocular Abnormalities Among Hemodialysis Patients in Indonesia
Background: This study aimed to identify the major ocular abnormality findings (i.e., cataract and conjunctival and corneal calcification (CCC)) among hemodialysis (HD) patients and their risk factors. Methods: A single institute-based cross-sectional study in Indonesia. Demographic data, medical hi...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2022-04-01
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| Series: | Acta Medica Indonesiana |
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| Online Access: | http://www.actamedindones.org/index.php/ijim/article/view/1950 |
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| author | Sauli Ari Widjaja Koichi Ono Yoshimune Hiratsuka Ima Yustiarini Widodo Widodo Akira Murakami |
| author_facet | Sauli Ari Widjaja Koichi Ono Yoshimune Hiratsuka Ima Yustiarini Widodo Widodo Akira Murakami |
| author_sort | Sauli Ari Widjaja |
| collection | DOAJ |
| description | Background: This study aimed to identify the major ocular abnormality findings (i.e., cataract and conjunctival and corneal calcification (CCC)) among hemodialysis (HD) patients and their risk factors. Methods: A single institute-based cross-sectional study in Indonesia. Demographic data, medical histories, and complete ocular examinations were collected. For two major ocular abnormalities found, a generalized estimating equation was incorporated in a logistic regression model to assess the relationship with their risk factors. Results: We analyzed 318 eyes (159 individuals), of which 54.7% male and 45.3% female. The mean age was 51.6±11.3 years. The mean HD period was 3.5±3.2 years. Hypertension and diabetes mellitus (DM) was found in 81.1% and 34.6%, respectively. The major ocular abnormalities found were cataract (206 eyes; 64.78% (95% CI 59.53-70.03)), followed by CCC (135 eyes; 42.45% (95 % CI 37.02-47.88)). In a multivariate model, higher education (odds ratio (OR) 0.17; 95% CI 0.04-0.74), hypertension (OR 0.15; 95% CI 0.03-0.79), DM (OR 10.49; 95% CI 1.57-70.06), Systolic Blood Pressure (SBP) 120-129 mmHg (OR 0.05; 95% CI 0.003-0.69), SBP >140 mmHg (OR 0.05; 95% CI 0.004-0.67), Diastolic Blood Pressure (DBP) 80-89 mmHg (OR 7.44; 95% CI 1.13-48.73), and DBP >90 mmHg (OR 48.47; 95% CI 3.4-692.03) showed significant association with cataract. Meanwhile, there was no significant association between CCC and any predictor. Conclusion: Cataract and CCC were found to be the major ocular abnormalities among HD patients in this study, with DM and higher DBP as the risk factors for cataract. This finding supports recommendations for integrated regular eye screening in HD patients.
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| format | Article |
| id | doaj-art-ecce32d8f5a44a059cadc91d6f5da3f9 |
| institution | DOAJ |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2022-04-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-ecce32d8f5a44a059cadc91d6f5da3f92025-08-20T03:11:36ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322022-04-01541488Major Ocular Abnormalities Among Hemodialysis Patients in IndonesiaSauli Ari Widjaja0Koichi Ono1Yoshimune Hiratsuka2Ima Yustiarini3Widodo Widodo4Akira Murakami51. Department of Ophthalmology, Juntendo University Graduate School of Medicine, Tokyo, Japan. 2. Department of Ophthalmology, Faculty of Medicine Universitas Airlangga - Dr. Soetomo Hospital, Surabaya, East Java, Indonesia.Department of Ophthalmology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, JapanDepartment of Ophthalmology, Juntendo University Graduate School of Medicine, Tokyo, JapanDepartment of Ophthalmology, Faculty of Medicine Universitas Airlangga - Dr. Soetomo Hospital, Surabaya, East Java, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Universitas Airlangga - Dr. Soetomo Hospital, Surabaya, East Java, IndonesiaDepartment of Ophthalmology, Juntendo University Graduate School of Medicine, Tokyo, JapanBackground: This study aimed to identify the major ocular abnormality findings (i.e., cataract and conjunctival and corneal calcification (CCC)) among hemodialysis (HD) patients and their risk factors. Methods: A single institute-based cross-sectional study in Indonesia. Demographic data, medical histories, and complete ocular examinations were collected. For two major ocular abnormalities found, a generalized estimating equation was incorporated in a logistic regression model to assess the relationship with their risk factors. Results: We analyzed 318 eyes (159 individuals), of which 54.7% male and 45.3% female. The mean age was 51.6±11.3 years. The mean HD period was 3.5±3.2 years. Hypertension and diabetes mellitus (DM) was found in 81.1% and 34.6%, respectively. The major ocular abnormalities found were cataract (206 eyes; 64.78% (95% CI 59.53-70.03)), followed by CCC (135 eyes; 42.45% (95 % CI 37.02-47.88)). In a multivariate model, higher education (odds ratio (OR) 0.17; 95% CI 0.04-0.74), hypertension (OR 0.15; 95% CI 0.03-0.79), DM (OR 10.49; 95% CI 1.57-70.06), Systolic Blood Pressure (SBP) 120-129 mmHg (OR 0.05; 95% CI 0.003-0.69), SBP >140 mmHg (OR 0.05; 95% CI 0.004-0.67), Diastolic Blood Pressure (DBP) 80-89 mmHg (OR 7.44; 95% CI 1.13-48.73), and DBP >90 mmHg (OR 48.47; 95% CI 3.4-692.03) showed significant association with cataract. Meanwhile, there was no significant association between CCC and any predictor. Conclusion: Cataract and CCC were found to be the major ocular abnormalities among HD patients in this study, with DM and higher DBP as the risk factors for cataract. This finding supports recommendations for integrated regular eye screening in HD patients. http://www.actamedindones.org/index.php/ijim/article/view/1950hemodialysisocular abnormalityocular manifestationchronic kidney diseasehealth-system |
| spellingShingle | Sauli Ari Widjaja Koichi Ono Yoshimune Hiratsuka Ima Yustiarini Widodo Widodo Akira Murakami Major Ocular Abnormalities Among Hemodialysis Patients in Indonesia Acta Medica Indonesiana hemodialysis ocular abnormality ocular manifestation chronic kidney disease health-system |
| title | Major Ocular Abnormalities Among Hemodialysis Patients in Indonesia |
| title_full | Major Ocular Abnormalities Among Hemodialysis Patients in Indonesia |
| title_fullStr | Major Ocular Abnormalities Among Hemodialysis Patients in Indonesia |
| title_full_unstemmed | Major Ocular Abnormalities Among Hemodialysis Patients in Indonesia |
| title_short | Major Ocular Abnormalities Among Hemodialysis Patients in Indonesia |
| title_sort | major ocular abnormalities among hemodialysis patients in indonesia |
| topic | hemodialysis ocular abnormality ocular manifestation chronic kidney disease health-system |
| url | http://www.actamedindones.org/index.php/ijim/article/view/1950 |
| work_keys_str_mv | AT sauliariwidjaja majorocularabnormalitiesamonghemodialysispatientsinindonesia AT koichiono majorocularabnormalitiesamonghemodialysispatientsinindonesia AT yoshimunehiratsuka majorocularabnormalitiesamonghemodialysispatientsinindonesia AT imayustiarini majorocularabnormalitiesamonghemodialysispatientsinindonesia AT widodowidodo majorocularabnormalitiesamonghemodialysispatientsinindonesia AT akiramurakami majorocularabnormalitiesamonghemodialysispatientsinindonesia |