Metabolic (cytoprotective) therapy of menopausal disturbances

The paper presents modern views on cardiovascular aspects of menopause and metabolic therapy of menopausal disturbances with meldonium (Mildronate®). The role of estrogen deficiency in climacteric disturbance development, key pathogenetic mechanisms of menopausal metabolic syndrome (MS), and relevan...

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Main Authors: S. N. Tolstov, V. B. Mychka
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2011-06-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1835
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author S. N. Tolstov
V. B. Mychka
author_facet S. N. Tolstov
V. B. Mychka
author_sort S. N. Tolstov
collection DOAJ
description The paper presents modern views on cardiovascular aspects of menopause and metabolic therapy of menopausal disturbances with meldonium (Mildronate®). The role of estrogen deficiency in climacteric disturbance development, key pathogenetic mechanisms of menopausal metabolic syndrome (MS), and relevant features of arterial hypertension and endothelial dysfunction development are discussed. The data on Mildronate® clinical use for cardiovascular prevention are summarized. The wide prevalence and multiple clinical manifestations of menopausal disturbances point to the need for their complex therapy. Mildronate® therapy is a new approach for systemic correction of metabolic disturbances in women with climacteric symptoms and menopausal MS.
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publishDate 2011-06-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-eccc6e6a5d2a4ebb95b2034826ba74442025-08-20T03:21:39Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252011-06-01103727510.15829/1728-8800-2011-3-72-751550Metabolic (cytoprotective) therapy of menopausal disturbancesS. N. Tolstov0V. B. Mychka1Saratov State Medical InstituteA.L. Myasnikov Research Institute of Clinical Cardiology, Russian Cardiology Scientific and Clinical ComplexThe paper presents modern views on cardiovascular aspects of menopause and metabolic therapy of menopausal disturbances with meldonium (Mildronate®). The role of estrogen deficiency in climacteric disturbance development, key pathogenetic mechanisms of menopausal metabolic syndrome (MS), and relevant features of arterial hypertension and endothelial dysfunction development are discussed. The data on Mildronate® clinical use for cardiovascular prevention are summarized. The wide prevalence and multiple clinical manifestations of menopausal disturbances point to the need for their complex therapy. Mildronate® therapy is a new approach for systemic correction of metabolic disturbances in women with climacteric symptoms and menopausal MS.https://cardiovascular.elpub.ru/jour/article/view/1835menopausemenopausal metabolic syndromearterial hypertensionmetabolic therapymildronate
spellingShingle S. N. Tolstov
V. B. Mychka
Metabolic (cytoprotective) therapy of menopausal disturbances
Кардиоваскулярная терапия и профилактика
menopause
menopausal metabolic syndrome
arterial hypertension
metabolic therapy
mildronate
title Metabolic (cytoprotective) therapy of menopausal disturbances
title_full Metabolic (cytoprotective) therapy of menopausal disturbances
title_fullStr Metabolic (cytoprotective) therapy of menopausal disturbances
title_full_unstemmed Metabolic (cytoprotective) therapy of menopausal disturbances
title_short Metabolic (cytoprotective) therapy of menopausal disturbances
title_sort metabolic cytoprotective therapy of menopausal disturbances
topic menopause
menopausal metabolic syndrome
arterial hypertension
metabolic therapy
mildronate
url https://cardiovascular.elpub.ru/jour/article/view/1835
work_keys_str_mv AT sntolstov metaboliccytoprotectivetherapyofmenopausaldisturbances
AT vbmychka metaboliccytoprotectivetherapyofmenopausaldisturbances