The Effects of Combined Micron-Scale Surface and Different Nanoscale Features on Cell Response

Sandblasting and acid-etching (SLA) and anodization are the two most commonly used methods for surface modification of biomedical titanium. However, there are unavoidable problems such as residual sand particles and lack of hydrophilicity on the surface of titanium sheets treated with SLA technology...

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Main Authors: Yi Kang, Xuelei Ren, Xin Yuan, Li Ma, Youneng Xie, Zeyu Bian, Jun Zuo, Xiyang Wang, Zhiming Yu, Kechao Zhou, Qiuping Wei
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Advances in Materials Science and Engineering
Online Access:http://dx.doi.org/10.1155/2018/6526913
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author Yi Kang
Xuelei Ren
Xin Yuan
Li Ma
Youneng Xie
Zeyu Bian
Jun Zuo
Xiyang Wang
Zhiming Yu
Kechao Zhou
Qiuping Wei
author_facet Yi Kang
Xuelei Ren
Xin Yuan
Li Ma
Youneng Xie
Zeyu Bian
Jun Zuo
Xiyang Wang
Zhiming Yu
Kechao Zhou
Qiuping Wei
author_sort Yi Kang
collection DOAJ
description Sandblasting and acid-etching (SLA) and anodization are the two most commonly used methods for surface modification of biomedical titanium. However, there are unavoidable problems such as residual sand particles and lack of hydrophilicity on the surface of titanium sheets treated with SLA technology. In addition, titanium implants showed only the micro/submicroscopic structure. In order to avoid the residue of sand particles in the surface of titanium, the two surface treatments etching treatment (E) and etched-anodizing (EA) on titanium were used, and their surface topography, surface chemistry, and surface roughness were compared with those of the SLA control group. Their wettability and the biocompatibility were also compared and evaluated. The results show that both E and EA samples have the micro/nano hierarchical structure and better wettability compared with the SLA samples. Their performances, especially the E surfaces, were enhanced in terms of cell adhesion, spreading, proliferation, and differentiation abilities.
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institution OA Journals
issn 1687-8434
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language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Advances in Materials Science and Engineering
spelling doaj-art-ecc421ec3f9442a6a73951d190f636152025-08-20T02:22:06ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422018-01-01201810.1155/2018/65269136526913The Effects of Combined Micron-Scale Surface and Different Nanoscale Features on Cell ResponseYi Kang0Xuelei Ren1Xin Yuan2Li Ma3Youneng Xie4Zeyu Bian5Jun Zuo6Xiyang Wang7Zhiming Yu8Kechao Zhou9Qiuping Wei10State Key Laboratory of Powder Metallurgy, School of Materials Science and Engineering, Central South University, Changsha 410083, ChinaState Key Laboratory of Powder Metallurgy, School of Materials Science and Engineering, Central South University, Changsha 410083, ChinaState Key Laboratory of Powder Metallurgy, School of Materials Science and Engineering, Central South University, Changsha 410083, ChinaState Key Laboratory of Powder Metallurgy, School of Materials Science and Engineering, Central South University, Changsha 410083, ChinaState Key Laboratory of Powder Metallurgy, School of Materials Science and Engineering, Central South University, Changsha 410083, ChinaState Key Laboratory of Powder Metallurgy, School of Materials Science and Engineering, Central South University, Changsha 410083, ChinaXiangya Stomatological Hospital, Central South University, Changsha 410078, ChinaHunan Engineering Laboratory of Advanced Artificial Osteo-Materials, Xiangya Hospital, Central South University, Changsha 410078, ChinaState Key Laboratory of Powder Metallurgy, School of Materials Science and Engineering, Central South University, Changsha 410083, ChinaState Key Laboratory of Powder Metallurgy, School of Materials Science and Engineering, Central South University, Changsha 410083, ChinaState Key Laboratory of Powder Metallurgy, School of Materials Science and Engineering, Central South University, Changsha 410083, ChinaSandblasting and acid-etching (SLA) and anodization are the two most commonly used methods for surface modification of biomedical titanium. However, there are unavoidable problems such as residual sand particles and lack of hydrophilicity on the surface of titanium sheets treated with SLA technology. In addition, titanium implants showed only the micro/submicroscopic structure. In order to avoid the residue of sand particles in the surface of titanium, the two surface treatments etching treatment (E) and etched-anodizing (EA) on titanium were used, and their surface topography, surface chemistry, and surface roughness were compared with those of the SLA control group. Their wettability and the biocompatibility were also compared and evaluated. The results show that both E and EA samples have the micro/nano hierarchical structure and better wettability compared with the SLA samples. Their performances, especially the E surfaces, were enhanced in terms of cell adhesion, spreading, proliferation, and differentiation abilities.http://dx.doi.org/10.1155/2018/6526913
spellingShingle Yi Kang
Xuelei Ren
Xin Yuan
Li Ma
Youneng Xie
Zeyu Bian
Jun Zuo
Xiyang Wang
Zhiming Yu
Kechao Zhou
Qiuping Wei
The Effects of Combined Micron-Scale Surface and Different Nanoscale Features on Cell Response
Advances in Materials Science and Engineering
title The Effects of Combined Micron-Scale Surface and Different Nanoscale Features on Cell Response
title_full The Effects of Combined Micron-Scale Surface and Different Nanoscale Features on Cell Response
title_fullStr The Effects of Combined Micron-Scale Surface and Different Nanoscale Features on Cell Response
title_full_unstemmed The Effects of Combined Micron-Scale Surface and Different Nanoscale Features on Cell Response
title_short The Effects of Combined Micron-Scale Surface and Different Nanoscale Features on Cell Response
title_sort effects of combined micron scale surface and different nanoscale features on cell response
url http://dx.doi.org/10.1155/2018/6526913
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