Plasmapheresis for refractory toxic epidermal necrolysis unresponsive to conventional therapy: a case report and literature review

Plasmapheresis for refractory toxic epidermal necrolysis unresponsive to conventional therapy: a case report and literature review

Toxic epidermal necrolysis (TEN) is a rare and life-threatening severe cutaneous adverse reaction. The conventional treatment approach includes immunomodulatory therapies, such as systemic corticosteroids, cyclosporine, intravenous immunoglobulin (IVIG), and tumor necrosis factor-alpha (TNF-α) inhib...

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Bibliographic Details
Main Authors: Shun-Qi Liao, Zhang-Rong Yan, Lun-Wei Lin, Ming Deng, Guo-Jin Xiao, Pei-Yang Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
toxic epidermal necrolysis
Steven Johnson syndrome
plasmapheresis
severe cutaneous adverse reaction
refractory
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1579349/full
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